Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid.
Although recombination is known to occur in foot-and-mouth disease virus (FMDV), it is considered only a minor determinant of virus sequence diversity. Analysis at phylogenetic scales shows inter-serotypic recombination events are rare, whereby recombination occurs almost exclusively in non-structur...
Main Authors: | Luca Ferretti, Eva Pérez-Martín, Fuquan Zhang, François Maree, Lin-Mari de Klerk-Lorist, Louis van Schalkwykc, Nicholas D Juleff, Bryan Charleston, Paolo Ribeca |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS Pathogens |
Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008235&type=printable |
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