Synergistic effect of collagenase-1 (MMP1), stromelysin-1 (MMP3) and gelatinase-B (MMP9) gene polymorphisms in breast cancer.

Synergistic effect of collagenase-1 (MMP1), stromelysin-1 (MMP3) and gelatinase-B (MMP9) gene polymorphisms in breast cancer.

Extracellular matrix degradation by matrix metalloproteinases (MMPs) is an important mechanism involved in tumor invasion and metastasis. Genetic variations of MMPs have shown association with multiple cancers. The present study is focused to elucidate the association of MMP-1, 3 and 9 genetic varia...

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Main Authors: Chiranjeevi Padala, Mohini Aiyengar Tupurani, Kaushik Puranam, Srilatha Gantala, Nivas Shyamala, Mrudula Spurthi Kondapalli, Kishore Kumar Gundapaneni, Saraswati Mudigonda, Rajesh Kumar Galimudi, Keerthi Kupsal, Santoshi Rani Nanchari, Uday Chavan, Sanjeeva Kumari Chinta, Srinivasulu Mukta, Vishnupriya Satti, Surekha Rani Hanumanth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5621673?pdf=render

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