Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation, and Local Immune Responses in IgA Nephropathy

Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation, and Local Immune Responses in IgA Nephropathy

Introduction: Numerous research works have shown that serum Gal-deficient (Gd) IgA1 levels are increased in IgA nephropathy (IgAN) patients and these levels are a dangerous risk factor for IgAN. A relationship between the gut microbiota and IgAN has been reported. Whether the gut microbiota particip...

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Bibliographic Details
Main Authors: Yuyan Tang, Yong Xiao, Haidong He, Yifan Zhu, Weiqian Sun, Ping Hu, Xudong Xu, Zhen Liu, Zhaowei Yan, Minggang Wei
Format: Article
Language:English
Published: Karger Publishers 2023-03-01
Series:Kidney & Blood Pressure Research
Subjects:
gut microbiome
iga nephropathy
gal-deficient iga1
permeability
inflammation
Online Access:https://www.karger.com/Article/FullText/528973

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