THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
Simulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall unde...
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Format: | Article |
Language: | English |
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Belgorod National Research University
2015-12-01
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Series: | Research Results in Pharmacology |
Subjects: | |
Online Access: | https://rrpharmacology.pensoft.net/article/31025/download/pdf/ |
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author | Vladimir Gureev Oksana Antseferova Tatyana Lokteva Alexandr Dolzhikov |
author_facet | Vladimir Gureev Oksana Antseferova Tatyana Lokteva Alexandr Dolzhikov |
author_sort | Vladimir Gureev |
collection | DOAJ |
description | Simulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall understanding of the pathogenesis of preeclampsia and placental insufficiency and create preconditions for development of new areas of creation of effective drugs for treatment and prevention of these pathologies. |
first_indexed | 2024-03-09T09:36:44Z |
format | Article |
id | doaj.art-6e3742fa5a8540fb9e54e9167482c1f7 |
institution | Directory Open Access Journal |
issn | 2658-381X |
language | English |
last_indexed | 2024-03-09T09:36:44Z |
publishDate | 2015-12-01 |
publisher | Belgorod National Research University |
record_format | Article |
series | Research Results in Pharmacology |
spelling | doaj.art-6e3742fa5a8540fb9e54e9167482c1f72023-12-02T01:41:18ZengBelgorod National Research UniversityResearch Results in Pharmacology2658-381X2015-12-0111343710.18413/2500-235X-2015-1-4-39-4431025THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENTVladimir GureevOksana AntseferovaTatyana LoktevaAlexandr DolzhikovSimulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall understanding of the pathogenesis of preeclampsia and placental insufficiency and create preconditions for development of new areas of creation of effective drugs for treatment and prevention of these pathologies.https://rrpharmacology.pensoft.net/article/31025/download/pdf/ratspreeclampsiaplacental insufficiencyplace |
spellingShingle | Vladimir Gureev Oksana Antseferova Tatyana Lokteva Alexandr Dolzhikov THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT Research Results in Pharmacology rats preeclampsia placental insufficiency place |
title | THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT |
title_full | THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT |
title_fullStr | THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT |
title_full_unstemmed | THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT |
title_short | THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT |
title_sort | effect of humoral factors released by hypoperfused placenta on fetal development |
topic | rats preeclampsia placental insufficiency place |
url | https://rrpharmacology.pensoft.net/article/31025/download/pdf/ |
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