THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT

Simulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall unde...

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Main Authors: Vladimir Gureev, Oksana Antseferova, Tatyana Lokteva, Alexandr Dolzhikov
Format: Article
Language:English
Published: Belgorod National Research University 2015-12-01
Series:Research Results in Pharmacology
Subjects:
Online Access:https://rrpharmacology.pensoft.net/article/31025/download/pdf/
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author Vladimir Gureev
Oksana Antseferova
Tatyana Lokteva
Alexandr Dolzhikov
author_facet Vladimir Gureev
Oksana Antseferova
Tatyana Lokteva
Alexandr Dolzhikov
author_sort Vladimir Gureev
collection DOAJ
description Simulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall understanding of the pathogenesis of preeclampsia and placental insufficiency and create preconditions for development of new areas of creation of effective drugs for treatment and prevention of these pathologies.
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spelling doaj.art-6e3742fa5a8540fb9e54e9167482c1f72023-12-02T01:41:18ZengBelgorod National Research UniversityResearch Results in Pharmacology2658-381X2015-12-0111343710.18413/2500-235X-2015-1-4-39-4431025THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENTVladimir GureevOksana AntseferovaTatyana LoktevaAlexandr DolzhikovSimulation of hypoperfusion of the right uterine horn in rats on the 14th day of pregnancy resulted in disruption of microcirculation in placentas of the left uterine horn, decrease of fetal weight and length as well as in fetal death after implantation. The obtained data complement the overall understanding of the pathogenesis of preeclampsia and placental insufficiency and create preconditions for development of new areas of creation of effective drugs for treatment and prevention of these pathologies.https://rrpharmacology.pensoft.net/article/31025/download/pdf/ratspreeclampsiaplacental insufficiencyplace
spellingShingle Vladimir Gureev
Oksana Antseferova
Tatyana Lokteva
Alexandr Dolzhikov
THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
Research Results in Pharmacology
rats
preeclampsia
placental insufficiency
place
title THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
title_full THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
title_fullStr THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
title_full_unstemmed THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
title_short THE EFFECT OF HUMORAL FACTORS RELEASED BY HYPOPERFUSED PLACENTA ON FETAL DEVELOPMENT
title_sort effect of humoral factors released by hypoperfused placenta on fetal development
topic rats
preeclampsia
placental insufficiency
place
url https://rrpharmacology.pensoft.net/article/31025/download/pdf/
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