Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis.

The function of the stem cell system is supported by a stereotypical shape of the niche structure. In Drosophila ovarian germarium, somatic cap cells form a dish-like niche structure that allows only two or three germ-line stem cells (GSCs) reside in the niche. Despite extensive studies on the mecha...

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Bibliographic Details
Main Authors: Kiichiro Taniguchi, Tatsushi Igaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010684