Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

Abstract Background Combination of statins and clopidogrel is frequently administered in patients with coronary artery disease (CAD). They are mainly activated and eliminated in the liver by cytochrome P450 isoenzyme 3A4 (CYP3A4). The aim was to clarify whether the coadministration of clopidogrel an...

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Bibliographic Details
Main Authors: Ke An, Rong Huang, Sai Tian, Dan Guo, Jiaqi Wang, Hongyan Lin, Shaohua Wang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Lipids in Health and Disease
Subjects:
Clopidogrel
Statins
Meta-analysis
Mortality
Platelet aggregation
Lipid
Online Access:http://link.springer.com/article/10.1186/s12944-019-1053-0

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