The rise of mechanical metamaterials: Auxetic constructs for skin wound healing
Auxetic materials are known for their unique ability to expand/contract in multiple directions when stretched/compressed. In other words, they exhibit a negative Poisson’s ratio, which is usually positive for most of materials. This behavior appears in some biological tissues such as human skin, whe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-06-01
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| Series: | Journal of Tissue Engineering |
| Online Access: | https://doi.org/10.1177/20417314231177838 |
| _version_ | 1827926772305362944 |
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| author | Óscar Lecina-Tejero María Ángeles Pérez Elena García-Gareta Carlos Borau |
| author_facet | Óscar Lecina-Tejero María Ángeles Pérez Elena García-Gareta Carlos Borau |
| author_sort | Óscar Lecina-Tejero |
| collection | DOAJ |
| description | Auxetic materials are known for their unique ability to expand/contract in multiple directions when stretched/compressed. In other words, they exhibit a negative Poisson’s ratio, which is usually positive for most of materials. This behavior appears in some biological tissues such as human skin, where it promotes wound healing by providing an enhanced mechanical support and facilitating cell migration. Skin tissue engineering has been a growing research topic in recent years, largely thanks to the rapid development of 3D printing techniques and technologies. The combination of computational studies with rapid manufacturing and tailored designs presents a huge potential for the future of personalized medicine. Overall, this review article provides a comprehensive overview of the current state of research on auxetic constructs for skin healing applications, highlighting the potential of auxetics as a promising treatment option for skin wounds. The article also identifies gaps in the current knowledge and suggests areas for future research. In particular, we discuss the designs, materials, manufacturing techniques, and also the computational and experimental studies on this topic. |
| first_indexed | 2024-03-13T05:43:46Z |
| format | Article |
| id | doaj.art-6e41f9fffacf4d2a8ff030912462e393 |
| institution | Directory Open Access Journal |
| issn | 2041-7314 |
| language | English |
| last_indexed | 2024-03-13T05:43:46Z |
| publishDate | 2023-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Tissue Engineering |
| spelling | doaj.art-6e41f9fffacf4d2a8ff030912462e3932023-06-13T21:03:59ZengSAGE PublishingJournal of Tissue Engineering2041-73142023-06-011410.1177/20417314231177838The rise of mechanical metamaterials: Auxetic constructs for skin wound healingÓscar Lecina-Tejero0María Ángeles Pérez1Elena García-Gareta2Carlos Borau3Multiscale in Mechanical and Biological Engineering, Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Aragon, SpainAragon Institute for Health Research (IIS Aragon), Miguel Servet University Hospital, 50009 Zaragoza, Aragon, SpainDivision of Biomaterials & Tissue Engineering, UCL Eastman Dental Institute, University College London, London, UKCentro Universitario de la Defensa de Zaragoza, Zaragoza, 50090, SpainAuxetic materials are known for their unique ability to expand/contract in multiple directions when stretched/compressed. In other words, they exhibit a negative Poisson’s ratio, which is usually positive for most of materials. This behavior appears in some biological tissues such as human skin, where it promotes wound healing by providing an enhanced mechanical support and facilitating cell migration. Skin tissue engineering has been a growing research topic in recent years, largely thanks to the rapid development of 3D printing techniques and technologies. The combination of computational studies with rapid manufacturing and tailored designs presents a huge potential for the future of personalized medicine. Overall, this review article provides a comprehensive overview of the current state of research on auxetic constructs for skin healing applications, highlighting the potential of auxetics as a promising treatment option for skin wounds. The article also identifies gaps in the current knowledge and suggests areas for future research. In particular, we discuss the designs, materials, manufacturing techniques, and also the computational and experimental studies on this topic.https://doi.org/10.1177/20417314231177838 |
| spellingShingle | Óscar Lecina-Tejero María Ángeles Pérez Elena García-Gareta Carlos Borau The rise of mechanical metamaterials: Auxetic constructs for skin wound healing Journal of Tissue Engineering |
| title | The rise of mechanical metamaterials: Auxetic constructs for skin wound healing |
| title_full | The rise of mechanical metamaterials: Auxetic constructs for skin wound healing |
| title_fullStr | The rise of mechanical metamaterials: Auxetic constructs for skin wound healing |
| title_full_unstemmed | The rise of mechanical metamaterials: Auxetic constructs for skin wound healing |
| title_short | The rise of mechanical metamaterials: Auxetic constructs for skin wound healing |
| title_sort | rise of mechanical metamaterials auxetic constructs for skin wound healing |
| url | https://doi.org/10.1177/20417314231177838 |
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