Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction

Abstract Introduction The aim of this study was to evaluate the measurements of corneal higher-order aberrations (HOAs) obtained by a new anterior segment optical coherence tomography (OCT) technique combined with a Placido topographer (the MS-39 device) in eyes with prior small-incision lenticule e...

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Main Authors: Rui Ning, Xiaomin Huang, Yili Jin, Chak Seng Lei, Xindi Ma, Shuoyu Xu, Jinxuan Xiahou, Giacomo Savini, Domenico Schiano-Lomoriello, Xiaoying Wang, Xingtao Zhou, Jinhai Huang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-03-01
Series:Ophthalmology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40123-023-00693-1
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author Rui Ning
Xiaomin Huang
Yili Jin
Chak Seng Lei
Xindi Ma
Shuoyu Xu
Jinxuan Xiahou
Giacomo Savini
Domenico Schiano-Lomoriello
Xiaoying Wang
Xingtao Zhou
Jinhai Huang
author_facet Rui Ning
Xiaomin Huang
Yili Jin
Chak Seng Lei
Xindi Ma
Shuoyu Xu
Jinxuan Xiahou
Giacomo Savini
Domenico Schiano-Lomoriello
Xiaoying Wang
Xingtao Zhou
Jinhai Huang
author_sort Rui Ning
collection DOAJ
description Abstract Introduction The aim of this study was to evaluate the measurements of corneal higher-order aberrations (HOAs) obtained by a new anterior segment optical coherence tomography (OCT) technique combined with a Placido topographer (the MS-39 device) in eyes with prior small-incision lenticule extraction (SMILE) and compare them to the measurements obtained by a Scheimpflug camera combined with a Placido topographer (the Sirius device). Methods A total of 56 eyes (56 patients) were included in this prospective study. Corneal aberrations were analyzed for the anterior, posterior, and total cornea surfaces. Within-subject standard deviation (S w), test–retest repeatability (TRT), and intraclass correlation coefficient (ICC) were used to assess the intraobserver repeatability and interobserver reproducibility. The differences were evaluated by paired t-test. Bland–Altman plots and 95% limits of agreement (95% LoA) were used to evaluate the agreement. Results High repeatability was observed for anterior and total corneal parameters, with S w value < 0.07, TRT ≤ 0.16, and ICCs > 0.893, but not trefoil. For the posterior corneal parameters, ICCs varied from 0.088 to 0.966. Regarding interobserver reproducibility, all S w values were ≤ 0.04 and TRT ≤ 0.11. ICCs ranged from 0.846 to 0.989, from 0.432 to 0.972, and from 0.798 to 0.985 for the anterior, total, and posterior corneal aberrations parameters, respectively. The mean difference in all aberrations was ≤ 0.05 μm. All parameters showed a narrow 95% LoA. Conclusion The MS-39 device achieved high precision in both anterior and total corneal measurements; the precision of posterior corneal higher-order RMS, astigmatism II, coma, and trefoil was lower. The two technologies used by the MS-39 and Sirius devices can be used interchangeably for measuring corneal HOAs after SMILE.
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spelling doaj.art-6e42129c71524f5bb133adfdde8578c02023-05-07T11:07:42ZengAdis, Springer HealthcareOphthalmology and Therapy2193-82452193-65282023-03-011231595161010.1007/s40123-023-00693-1Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule ExtractionRui Ning0Xiaomin Huang1Yili Jin2Chak Seng Lei3Xindi Ma4Shuoyu Xu5Jinxuan Xiahou6Giacomo Savini7Domenico Schiano-Lomoriello8Xiaoying Wang9Xingtao Zhou10Jinhai Huang11Eye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityG.B. Bietti Foundation I.R.C.C.S.G.B. Bietti Foundation I.R.C.C.S.Eye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan UniversityAbstract Introduction The aim of this study was to evaluate the measurements of corneal higher-order aberrations (HOAs) obtained by a new anterior segment optical coherence tomography (OCT) technique combined with a Placido topographer (the MS-39 device) in eyes with prior small-incision lenticule extraction (SMILE) and compare them to the measurements obtained by a Scheimpflug camera combined with a Placido topographer (the Sirius device). Methods A total of 56 eyes (56 patients) were included in this prospective study. Corneal aberrations were analyzed for the anterior, posterior, and total cornea surfaces. Within-subject standard deviation (S w), test–retest repeatability (TRT), and intraclass correlation coefficient (ICC) were used to assess the intraobserver repeatability and interobserver reproducibility. The differences were evaluated by paired t-test. Bland–Altman plots and 95% limits of agreement (95% LoA) were used to evaluate the agreement. Results High repeatability was observed for anterior and total corneal parameters, with S w value < 0.07, TRT ≤ 0.16, and ICCs > 0.893, but not trefoil. For the posterior corneal parameters, ICCs varied from 0.088 to 0.966. Regarding interobserver reproducibility, all S w values were ≤ 0.04 and TRT ≤ 0.11. ICCs ranged from 0.846 to 0.989, from 0.432 to 0.972, and from 0.798 to 0.985 for the anterior, total, and posterior corneal aberrations parameters, respectively. The mean difference in all aberrations was ≤ 0.05 μm. All parameters showed a narrow 95% LoA. Conclusion The MS-39 device achieved high precision in both anterior and total corneal measurements; the precision of posterior corneal higher-order RMS, astigmatism II, coma, and trefoil was lower. The two technologies used by the MS-39 and Sirius devices can be used interchangeably for measuring corneal HOAs after SMILE.https://doi.org/10.1007/s40123-023-00693-1AgreementHigher-order aberrationsOptical coherence tomography-PlacidoSmall-incision lenticule extraction
spellingShingle Rui Ning
Xiaomin Huang
Yili Jin
Chak Seng Lei
Xindi Ma
Shuoyu Xu
Jinxuan Xiahou
Giacomo Savini
Domenico Schiano-Lomoriello
Xiaoying Wang
Xingtao Zhou
Jinhai Huang
Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
Ophthalmology and Therapy
Agreement
Higher-order aberrations
Optical coherence tomography-Placido
Small-incision lenticule extraction
title Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
title_full Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
title_fullStr Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
title_full_unstemmed Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
title_short Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction
title_sort corneal higher order aberrations measurements precision of sd oct placido topography and comparison with a scheimpflug placido topography in eyes after small incision lenticule extraction
topic Agreement
Higher-order aberrations
Optical coherence tomography-Placido
Small-incision lenticule extraction
url https://doi.org/10.1007/s40123-023-00693-1
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