Gelatin-containing porous polycaprolactone PolyHIPEs as substrates for 3D breast cancer cell culture and vascular infiltration

Gelatin-containing porous polycaprolactone PolyHIPEs as substrates for 3D breast cancer cell culture and vascular infiltration

Tumour survival and growth are reliant on angiogenesis, the formation of new blood vessels, to facilitate nutrient and waste exchange and, importantly, provide a route for metastasis from a primary to a secondary site. Whilst current models can ensure the transport and exchange of nutrients and wast...

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Bibliographic Details
Main Authors: Caitlin E. Jackson, Iona Doyle, Hamood Khan, Samuel F. Williams, Betül Aldemir Dikici, Edgar Barajas Ledesma, Helen E. Bryant, William R. English, Nicola H. Green, Frederik Claeyssens
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
gelatin
polyHIPE
CAM assay
PCL (polycaprolactone)
vascularisation
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1321197/full

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