Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus
Background: This study aimed to explore the effect of 5-HT1A receptors (HTR1A) on activation of the anterior cingulate cortex and simultaneous regulation of neural activity in the insular cortex and hippocampus.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2020-10-01
|
| Series: | Pteridines |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/pteridines-2020-0016 |
| _version_ | 1797987696861249536 |
|---|---|
| author | Xuan Liqian Zhou Jingjing Yi Lisha Xu Shuchang |
| author_facet | Xuan Liqian Zhou Jingjing Yi Lisha Xu Shuchang |
| author_sort | Xuan Liqian |
| collection | DOAJ |
| description | Background: This study aimed to explore the effect of 5-HT1A receptors (HTR1A) on activation of the anterior cingulate cortex and simultaneous regulation of neural activity in the insular cortex and hippocampus. |
| first_indexed | 2024-04-11T07:51:36Z |
| format | Article |
| id | doaj.art-6e454af2704f4193bad4e5c3fb9d53a2 |
| institution | Directory Open Access Journal |
| issn | 0933-4807 2195-4720 |
| language | English |
| last_indexed | 2024-04-11T07:51:36Z |
| publishDate | 2020-10-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Pteridines |
| spelling | doaj.art-6e454af2704f4193bad4e5c3fb9d53a22022-12-22T04:36:03ZengDe GruyterPteridines0933-48072195-47202020-10-0131116517310.1515/pteridines-2020-0016pteridines-2020-0016Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampusXuan Liqian0Zhou Jingjing1Yi Lisha2Xu Shuchang3Digestive Endoscopy Center, Department of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDigestive Endoscopy Center, Department of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai, ChinaBackground: This study aimed to explore the effect of 5-HT1A receptors (HTR1A) on activation of the anterior cingulate cortex and simultaneous regulation of neural activity in the insular cortex and hippocampus.https://doi.org/10.1515/pteridines-2020-0016irritable bowel syndromvisceral hypersensitivity5-ht1a receptorcentral nervous systemlimbic system |
| spellingShingle | Xuan Liqian Zhou Jingjing Yi Lisha Xu Shuchang Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus Pteridines irritable bowel syndrom visceral hypersensitivity 5-ht1a receptor central nervous system limbic system |
| title | Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus |
| title_full | Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus |
| title_fullStr | Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus |
| title_full_unstemmed | Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus |
| title_short | Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus |
| title_sort | up regulation of htr1a reverses stress induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex insular cortex and hippocampus |
| topic | irritable bowel syndrom visceral hypersensitivity 5-ht1a receptor central nervous system limbic system |
| url | https://doi.org/10.1515/pteridines-2020-0016 |
| work_keys_str_mv | AT xuanliqian upregulationofhtr1areversesstressinducedvisceralhypersensitivitythroughmodulatinginteractionsamongtheanteriorcingulatecortexinsularcortexandhippocampus AT zhoujingjing upregulationofhtr1areversesstressinducedvisceralhypersensitivitythroughmodulatinginteractionsamongtheanteriorcingulatecortexinsularcortexandhippocampus AT yilisha upregulationofhtr1areversesstressinducedvisceralhypersensitivitythroughmodulatinginteractionsamongtheanteriorcingulatecortexinsularcortexandhippocampus AT xushuchang upregulationofhtr1areversesstressinducedvisceralhypersensitivitythroughmodulatinginteractionsamongtheanteriorcingulatecortexinsularcortexandhippocampus |