Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation

Background and aim Pseudoexfoliation (PEX) syndrome is an age-related ocular disorder that is known to be linked with early development of cataract. Phacoemulsification, a cataract surgery, is thought to carry higher risk of complication in patients with PEX. This study aimed to evaluate the corneal...

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Main Authors: Hassan S Yousef, Ibrahim Amer, Shymaa A.A Thabet
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Al-Azhar Assiut Medical Journal
Subjects:
Online Access:http://www.azmj.eg.net/article.asp?issn=1687-1693;year=2022;volume=20;issue=4;spage=314;epage=318;aulast=Yousef
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author Hassan S Yousef
Ibrahim Amer
Shymaa A.A Thabet
author_facet Hassan S Yousef
Ibrahim Amer
Shymaa A.A Thabet
author_sort Hassan S Yousef
collection DOAJ
description Background and aim Pseudoexfoliation (PEX) syndrome is an age-related ocular disorder that is known to be linked with early development of cataract. Phacoemulsification, a cataract surgery, is thought to carry higher risk of complication in patients with PEX. This study aimed to evaluate the corneal endothelial cell changes before and after phacoemulsification in pseudoexfoliative patients relative to healthy adults. Patients and methods In total, 100 eyes of 100 patients were enrolled in this prospective nonrandomized study who were divided into two groups (PEX and non-PEX patients). All participants were subjected to ocular examination with specular microscopy before and after phacoemulsification. Data for corneal endothelial cell density (ECD), coefficient of variation (CV), and hexagonal cells were recorded before operation and at 1 week, 1 month, and 6 months postoperative. Results No significant difference was detected between the two studied groups regarding ECD, CV, and hexagonality either preoperatively or postoperatively at 1 week, 1 month, and 6 months. However, a significant difference between preoperative and postoperative data of ECD, CV, and hexagonality was detected in each group. Conclusion Despite the previous conviction that phacoemulsification surgery carries more risks in eyes with PEX, the results of this study prove that phacoemulsification is a safe choice in these eyes without a higher rate of postoperative complications.
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spelling doaj.art-6e459cbdc63e47f3bead33d1fa9ad7d62024-03-25T09:58:56ZengWolters Kluwer Medknow PublicationsAl-Azhar Assiut Medical Journal1687-16932022-01-0120431431810.4103/azmj.azmj_128_21Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliationHassan S YousefIbrahim AmerShymaa A.A ThabetBackground and aim Pseudoexfoliation (PEX) syndrome is an age-related ocular disorder that is known to be linked with early development of cataract. Phacoemulsification, a cataract surgery, is thought to carry higher risk of complication in patients with PEX. This study aimed to evaluate the corneal endothelial cell changes before and after phacoemulsification in pseudoexfoliative patients relative to healthy adults. Patients and methods In total, 100 eyes of 100 patients were enrolled in this prospective nonrandomized study who were divided into two groups (PEX and non-PEX patients). All participants were subjected to ocular examination with specular microscopy before and after phacoemulsification. Data for corneal endothelial cell density (ECD), coefficient of variation (CV), and hexagonal cells were recorded before operation and at 1 week, 1 month, and 6 months postoperative. Results No significant difference was detected between the two studied groups regarding ECD, CV, and hexagonality either preoperatively or postoperatively at 1 week, 1 month, and 6 months. However, a significant difference between preoperative and postoperative data of ECD, CV, and hexagonality was detected in each group. Conclusion Despite the previous conviction that phacoemulsification surgery carries more risks in eyes with PEX, the results of this study prove that phacoemulsification is a safe choice in these eyes without a higher rate of postoperative complications.http://www.azmj.eg.net/article.asp?issn=1687-1693;year=2022;volume=20;issue=4;spage=314;epage=318;aulast=Yousefcataractcoefficient of variationcorneal endothelial cellshexagonal cellsphacoemulsificationpseudoexfoliation
spellingShingle Hassan S Yousef
Ibrahim Amer
Shymaa A.A Thabet
Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
Al-Azhar Assiut Medical Journal
cataract
coefficient of variation
corneal endothelial cells
hexagonal cells
phacoemulsification
pseudoexfoliation
title Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
title_full Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
title_fullStr Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
title_full_unstemmed Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
title_short Specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
title_sort specular microscopic changes of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation
topic cataract
coefficient of variation
corneal endothelial cells
hexagonal cells
phacoemulsification
pseudoexfoliation
url http://www.azmj.eg.net/article.asp?issn=1687-1693;year=2022;volume=20;issue=4;spage=314;epage=318;aulast=Yousef
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AT ibrahimamer specularmicroscopicchangesofcornealendothelialcellsafterphacoemulsificationinpatientswithpseudoexfoliation
AT shymaaaathabet specularmicroscopicchangesofcornealendothelialcellsafterphacoemulsificationinpatientswithpseudoexfoliation