Expressing the Pro-Apoptotic Reaper Protein via Insertion into the Structural Open Reading Frame of Sindbis Virus Reduces the Ability to Infect <i>Aedes aegypti</i> Mosquitoes

Expressing the Pro-Apoptotic Reaper Protein via Insertion into the Structural Open Reading Frame of Sindbis Virus Reduces the Ability to Infect <i>Aedes aegypti</i> Mosquitoes

Arboviruses continue to threaten a significant portion of the human population, and a better understanding is needed of the determinants of successful arbovirus infection of arthropod vectors. Avoiding apoptosis has been shown to be one such determinant. Previous work showed that a Sindbis virus (SI...

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Bibliographic Details
Main Authors: Alexis Carpenter, Scott R. Santos, Rollie J. Clem
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
apoptosis
Sindbis virus
arbovirus
alphavirus
antiviral immunity
mosquito
Online Access:https://www.mdpi.com/1999-4915/14/9/2035

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