Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease. Inferring disease biology from these observations, however, hinges on our ability to discover the molecular processes being perturbed by these risk...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Elizabeth J Rossin, Kasper Lage, Soumya Raychaudhuri, Ramnik J Xavier, Diana Tatar, Yair Benita, International Inflammatory Bowel Disease Genetics Constortium, Chris Cotsapas, Mark J Daly
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2011-01-01
श्रृंखला:PLoS Genetics
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC3020935?pdf=render