Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.
Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease. Inferring disease biology from these observations, however, hinges on our ability to discover the molecular processes being perturbed by these risk...
मुख्य लेखकों: | , , , , , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
Public Library of Science (PLoS)
2011-01-01
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श्रृंखला: | PLoS Genetics |
ऑनलाइन पहुंच: | http://europepmc.org/articles/PMC3020935?pdf=render |