Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel
Nutrient deficiencies in humans are problematic on a global scale but are more prevalent in regions where high-quality and nutrient-dense foods are scarce. Developing nutrient-rich crops that thrive in these regions of the world would help alleviate the disparity. We leveraged the wild barley (<i...
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| Format: | Article |
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MDPI AG
2022-11-01
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| Series: | Agronomy |
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| Online Access: | https://www.mdpi.com/2073-4395/12/11/2839 |
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| author | Jillian A. Abendroth Ahmad H. Sallam Brian J. Steffenson Marcus A. Vinje Ramamurthy Mahalingam Jason G. Walling |
| author_facet | Jillian A. Abendroth Ahmad H. Sallam Brian J. Steffenson Marcus A. Vinje Ramamurthy Mahalingam Jason G. Walling |
| author_sort | Jillian A. Abendroth |
| collection | DOAJ |
| description | Nutrient deficiencies in humans are problematic on a global scale but are more prevalent in regions where high-quality and nutrient-dense foods are scarce. Developing nutrient-rich crops that thrive in these regions of the world would help alleviate the disparity. We leveraged the wild barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Collection (WBDC) (N = 232) to characterize the variation in seed macronutrient (P, K, Ca, and Mg) and micronutrient (B, Cu, Fe, Mn, and Zn) contents found in this subspecies and to reveal chromosomal regions associated with these traits. Most micro- and macronutrients displayed variation in the WBDC and, except for boron and phosphorous, had a modest level of heritability (>0.5). Variation due to environment was significant (<i>p</i> < 0.001) for each element, except iron, and genotype was significant for all the tested nutrients, except boron. Thirty-seven marker–trait associations (MTAs) were detected for three (K, Ca, and Mg) of the four macro- and four (Cu, Fe, Mn, and Zn) of the five micronutrients. Several compelling candidate genes harbored within MTAs were also identified, including ABC transporters, NAC transcription factors, and bZIP transcription factors. |
| first_indexed | 2024-03-09T18:32:15Z |
| format | Article |
| id | doaj.art-6e4d914da1594a95b36c0fc1b9442b86 |
| institution | Directory Open Access Journal |
| issn | 2073-4395 |
| language | English |
| last_indexed | 2024-03-09T18:32:15Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Agronomy |
| spelling | doaj.art-6e4d914da1594a95b36c0fc1b9442b862023-11-24T07:26:26ZengMDPI AGAgronomy2073-43952022-11-011211283910.3390/agronomy12112839Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity PanelJillian A. Abendroth0Ahmad H. Sallam1Brian J. Steffenson2Marcus A. Vinje3Ramamurthy Mahalingam4Jason G. Walling5USDA-ARS, Cereal Crops Research Unit, 502 Walnut Street, Madison, WI 53726, USADepartment of Plant Pathology, University of Minnesota, St. Paul, MN 55108, USADepartment of Plant Pathology, University of Minnesota, St. Paul, MN 55108, USAUSDA-ARS, Cereal Crops Research Unit, 502 Walnut Street, Madison, WI 53726, USAUSDA-ARS, Cereal Crops Research Unit, 502 Walnut Street, Madison, WI 53726, USAUSDA-ARS, Cereal Crops Research Unit, 502 Walnut Street, Madison, WI 53726, USANutrient deficiencies in humans are problematic on a global scale but are more prevalent in regions where high-quality and nutrient-dense foods are scarce. Developing nutrient-rich crops that thrive in these regions of the world would help alleviate the disparity. We leveraged the wild barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Collection (WBDC) (N = 232) to characterize the variation in seed macronutrient (P, K, Ca, and Mg) and micronutrient (B, Cu, Fe, Mn, and Zn) contents found in this subspecies and to reveal chromosomal regions associated with these traits. Most micro- and macronutrients displayed variation in the WBDC and, except for boron and phosphorous, had a modest level of heritability (>0.5). Variation due to environment was significant (<i>p</i> < 0.001) for each element, except iron, and genotype was significant for all the tested nutrients, except boron. Thirty-seven marker–trait associations (MTAs) were detected for three (K, Ca, and Mg) of the four macro- and four (Cu, Fe, Mn, and Zn) of the five micronutrients. Several compelling candidate genes harbored within MTAs were also identified, including ABC transporters, NAC transcription factors, and bZIP transcription factors.https://www.mdpi.com/2073-4395/12/11/2839genome-wide associationmicronutrientsbarleyhordeumspontaneum |
| spellingShingle | Jillian A. Abendroth Ahmad H. Sallam Brian J. Steffenson Marcus A. Vinje Ramamurthy Mahalingam Jason G. Walling Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel Agronomy genome-wide association micronutrients barley hordeum spontaneum |
| title | Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel |
| title_full | Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel |
| title_fullStr | Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel |
| title_full_unstemmed | Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel |
| title_short | Identification of Genomic Loci Controlling Grain Macro and Micronutrient Variation in a Wild Barley (<i>Hordeum vulgare</i> spp. <i>spontaneum</i>) Diversity Panel |
| title_sort | identification of genomic loci controlling grain macro and micronutrient variation in a wild barley i hordeum vulgare i spp i spontaneum i diversity panel |
| topic | genome-wide association micronutrients barley hordeum spontaneum |
| url | https://www.mdpi.com/2073-4395/12/11/2839 |
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