Genetic and Epigenetic Profiles of Polycystic Ovarian Syndrome and In Vitro Bisphenol Exposure in a Human Granulosa Cell Model

Genetic and Epigenetic Profiles of Polycystic Ovarian Syndrome and In Vitro Bisphenol Exposure in a Human Granulosa Cell Model

Higher levels of bisphenols are found in granulosa cells of women with polycystic ovary syndrome (PCOS), posing the question: Is bisphenol exposure linked to PCOS pathophysiology? Human granulosa cells were obtained from women with and without PCOS, and genes and microRNAs associated with PCOS were...

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Bibliographic Details
Main Authors: Reem Sabry, Jenna F. Gallo, Charlie Rooney, Olivia L. M. Scandlan, Ola S. Davis, Shilpa Amin, Mehrnoosh Faghih, Megan Karnis, Michael S. Neal, Laura A. Favetta
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
polycystic ovary syndrome
endocrine disrupting compounds
bisphenols
granulosa cells
microRNAs
Online Access:https://www.mdpi.com/2227-9059/12/1/237

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