Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature
Malignant proliferation of plasma cells arising outside the bone marrow or osseous sites is known as extramedullary plasmacytoma. Solitary Extramedullary Plasmacytoma (SEP) are commonly located in upper respiratory tract and sinuses. Involvement of lower respiratory tract is rarely seen in case of S...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2023-05-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/17935/60394_CE[Ra1]_F_(IS)_PF1(AKA_KM)_PFA(AKA_KM)_PN(KM).pdf |
| _version_ | 1797818571267506176 |
|---|---|
| author | Rakhi Verma Ajeet Kumar Gandhi Anoop Srivastava Pradyumn Singh Madhup Rastogi |
| author_facet | Rakhi Verma Ajeet Kumar Gandhi Anoop Srivastava Pradyumn Singh Madhup Rastogi |
| author_sort | Rakhi Verma |
| collection | DOAJ |
| description | Malignant proliferation of plasma cells arising outside the bone marrow or osseous sites is known as extramedullary plasmacytoma. Solitary Extramedullary Plasmacytoma (SEP) are commonly located in upper respiratory tract and sinuses. Involvement of lower respiratory tract is rarely seen in case of SEP. Here, the authors report a case of endobronchial plasmacytoma in a 41-year-old male patient, without any medical risk factors presenting with complaint of blood stained sputum. Radiological imaging confirmed endobronchial mass in right main bronchus. Histopathology with immunohistochemistry confirmed the diagnosis of plasmacytoma. Work-up for multiple myeloma was negative. Thus, patient was subsequently planned for radical radiotherapy for the primary disease. The patient tolerated the treatment well and was asymptomatic at the time of last follow-up. Solitary Endobronchial Plasmacytoma (SBP) is a rare presentation of SEP. Radical radiotherapy yields excellent local control rates and symptomatic benefit. Close surveillance for development of multiple myeloma is required at periodic intervals. |
| first_indexed | 2024-03-13T09:09:51Z |
| format | Article |
| id | doaj.art-6e507feac5f44e5aa365e87d4fc160c1 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-13T09:09:51Z |
| publishDate | 2023-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-6e507feac5f44e5aa365e87d4fc160c12023-05-27T09:43:02ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-05-01175XD04XD0610.7860/JCDR/2023/60394.17935Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of LiteratureRakhi Verma0Ajeet Kumar Gandhi1Anoop Srivastava2Pradyumn Singh3Madhup Rastogi4Resident, Department of Radiation Oncology, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.Associate Professor, Department of Radiation Oncology, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.Professor, Department of Radiation Oncology, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.Professor, Department of Pathology, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.Professor, Department of Radiation Oncology, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.Malignant proliferation of plasma cells arising outside the bone marrow or osseous sites is known as extramedullary plasmacytoma. Solitary Extramedullary Plasmacytoma (SEP) are commonly located in upper respiratory tract and sinuses. Involvement of lower respiratory tract is rarely seen in case of SEP. Here, the authors report a case of endobronchial plasmacytoma in a 41-year-old male patient, without any medical risk factors presenting with complaint of blood stained sputum. Radiological imaging confirmed endobronchial mass in right main bronchus. Histopathology with immunohistochemistry confirmed the diagnosis of plasmacytoma. Work-up for multiple myeloma was negative. Thus, patient was subsequently planned for radical radiotherapy for the primary disease. The patient tolerated the treatment well and was asymptomatic at the time of last follow-up. Solitary Endobronchial Plasmacytoma (SBP) is a rare presentation of SEP. Radical radiotherapy yields excellent local control rates and symptomatic benefit. Close surveillance for development of multiple myeloma is required at periodic intervals.https://www.jcdr.net/articles/PDF/17935/60394_CE[Ra1]_F_(IS)_PF1(AKA_KM)_PFA(AKA_KM)_PN(KM).pdfmalignant proliferationright bronchusupper respiratory tract |
| spellingShingle | Rakhi Verma Ajeet Kumar Gandhi Anoop Srivastava Pradyumn Singh Madhup Rastogi Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature Journal of Clinical and Diagnostic Research malignant proliferation right bronchus upper respiratory tract |
| title | Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature |
| title_full | Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature |
| title_fullStr | Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature |
| title_full_unstemmed | Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature |
| title_short | Primary Endobronchial Plasmacytoma with Mediastinal Lymph Nodes treated with Radical Radiotherapy: A Case Report with Review of Literature |
| title_sort | primary endobronchial plasmacytoma with mediastinal lymph nodes treated with radical radiotherapy a case report with review of literature |
| topic | malignant proliferation right bronchus upper respiratory tract |
| url | https://www.jcdr.net/articles/PDF/17935/60394_CE[Ra1]_F_(IS)_PF1(AKA_KM)_PFA(AKA_KM)_PN(KM).pdf |
| work_keys_str_mv | AT rakhiverma primaryendobronchialplasmacytomawithmediastinallymphnodestreatedwithradicalradiotherapyacasereportwithreviewofliterature AT ajeetkumargandhi primaryendobronchialplasmacytomawithmediastinallymphnodestreatedwithradicalradiotherapyacasereportwithreviewofliterature AT anoopsrivastava primaryendobronchialplasmacytomawithmediastinallymphnodestreatedwithradicalradiotherapyacasereportwithreviewofliterature AT pradyumnsingh primaryendobronchialplasmacytomawithmediastinallymphnodestreatedwithradicalradiotherapyacasereportwithreviewofliterature AT madhuprastogi primaryendobronchialplasmacytomawithmediastinallymphnodestreatedwithradicalradiotherapyacasereportwithreviewofliterature |