NUP214 fusion genes in acute leukemias: genetic characterization of rare cases

NUP214 fusion genes in acute leukemias: genetic characterization of rare cases

IntroductionAlterations of the NUP214 gene (9q34) are recurrent in acute leukemias. Rearrangements of chromosomal band 9q34 targeting this locus can be karyotypically distinct, for example t(6;9)(p22;q34)/DEK::NUP214, or cryptic, in which case no visible change of 9q34 is seen by chromosome banding....

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Bibliographic Details
Main Authors: Marta Brunetti, Kristin Andersen, Signe Spetalen, Andrea Lenartova, Liv Toril Nygård Osnes, Helen Vålerhaugen, Sverre Heim, Francesca Micci
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
acute leukemias
rare leukemias
cytogenetics
9q34-NUP214
fluorescence in situ hybridization
array comparative genomic hybridization
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1371980/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1371980/full

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