Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke
Acute ischemic stroke (AIS) is one of the leading diseases causing death and disability worldwide, and treatment options remain very limited. Traditional Chinese Medicine (TCM) has been used for thousands of years to treat ischemic stroke and has been proven to have significant efficacy, but its mec...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1164150/full |
| _version_ | 1827968010981212160 |
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| author | Lin Gao Lin Gao Xiuwen Xia Yinqi Shuai Yinqi Shuai Hong Zhang Wei Jin Xiaoyun Zhang Yi Zhang |
| author_facet | Lin Gao Lin Gao Xiuwen Xia Yinqi Shuai Yinqi Shuai Hong Zhang Wei Jin Xiaoyun Zhang Yi Zhang |
| author_sort | Lin Gao |
| collection | DOAJ |
| description | Acute ischemic stroke (AIS) is one of the leading diseases causing death and disability worldwide, and treatment options remain very limited. Traditional Chinese Medicine (TCM) has been used for thousands of years to treat ischemic stroke and has been proven to have significant efficacy, but its mechanism of action is still unclear. As research related to the brain-gut-microbe axis progresses, there is increasing evidence that the gut microbiota plays an important role during AIS. The interaction between TCM and the gut microbiota has been suggested as a possible key link to the therapeutic effects of TCM. We have compiled and reviewed recent studies on the relationship between AIS, TCM, and gut microbiota, with the expectation of providing more ideas to elucidate the mechanism of action of TCM in the treatment of AIS. |
| first_indexed | 2024-04-09T18:14:34Z |
| format | Article |
| id | doaj.art-6e553aa01e964bf4abeec85d9320413f |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-09T18:14:34Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-6e553aa01e964bf4abeec85d9320413f2023-04-13T05:21:13ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-04-011410.3389/fphar.2023.11641501164150Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic strokeLin Gao0Lin Gao1Xiuwen Xia2Yinqi Shuai3Yinqi Shuai4Hong Zhang5Wei Jin6Xiaoyun Zhang7Yi Zhang8Emergency Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaEmergency Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaEmergency Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaEmergency Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaEmergency Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaGeriatric Department, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu, Sichuan, ChinaAcute ischemic stroke (AIS) is one of the leading diseases causing death and disability worldwide, and treatment options remain very limited. Traditional Chinese Medicine (TCM) has been used for thousands of years to treat ischemic stroke and has been proven to have significant efficacy, but its mechanism of action is still unclear. As research related to the brain-gut-microbe axis progresses, there is increasing evidence that the gut microbiota plays an important role during AIS. The interaction between TCM and the gut microbiota has been suggested as a possible key link to the therapeutic effects of TCM. We have compiled and reviewed recent studies on the relationship between AIS, TCM, and gut microbiota, with the expectation of providing more ideas to elucidate the mechanism of action of TCM in the treatment of AIS.https://www.frontiersin.org/articles/10.3389/fphar.2023.1164150/fullacute ischemic stroke (AIS)traditional Chinese medicine (TCM)gut microbiotaChinese herbsbrain-gut-microbe axis (BGMAs)immunology and inflammation |
| spellingShingle | Lin Gao Lin Gao Xiuwen Xia Yinqi Shuai Yinqi Shuai Hong Zhang Wei Jin Xiaoyun Zhang Yi Zhang Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke Frontiers in Pharmacology acute ischemic stroke (AIS) traditional Chinese medicine (TCM) gut microbiota Chinese herbs brain-gut-microbe axis (BGMAs) immunology and inflammation |
| title | Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke |
| title_full | Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke |
| title_fullStr | Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke |
| title_full_unstemmed | Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke |
| title_short | Gut microbiota, a hidden protagonist of traditional Chinese medicine for acute ischemic stroke |
| title_sort | gut microbiota a hidden protagonist of traditional chinese medicine for acute ischemic stroke |
| topic | acute ischemic stroke (AIS) traditional Chinese medicine (TCM) gut microbiota Chinese herbs brain-gut-microbe axis (BGMAs) immunology and inflammation |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1164150/full |
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