α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium

α-Gal syndrome (AGS) is an allergy to meat and other products derived from non-primate mammals resulting from development of IgE antibodies against the oligosaccharide galactose-α,1,3-galactose (α-Gal). Sensitivity to α-Gal is linked to tick bites, particularly bites from Amblyomma americanum (lone...

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Main Authors: Andrew Hawkins, Jeffrey M Wilson, Robert B. Hawkins, Christopher Moskaluk, Rung Chi Li, Margaret Tracci
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Annals of Vascular Surgery - Brief Reports and Innovations
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S277268782300034X
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author Andrew Hawkins
Jeffrey M Wilson
Robert B. Hawkins
Christopher Moskaluk
Rung Chi Li
Margaret Tracci
author_facet Andrew Hawkins
Jeffrey M Wilson
Robert B. Hawkins
Christopher Moskaluk
Rung Chi Li
Margaret Tracci
author_sort Andrew Hawkins
collection DOAJ
description α-Gal syndrome (AGS) is an allergy to meat and other products derived from non-primate mammals resulting from development of IgE antibodies against the oligosaccharide galactose-α,1,3-galactose (α-Gal). Sensitivity to α-Gal is linked to tick bites, particularly bites from Amblyomma americanum (lone star tick). Recent studies demonstrate early failure of bioprosthetic valves in the setting of chronic inflammation following exposure to animal-derived surgical implants. We report a case of AGS associated with restenosis of prior bovine pericardium used for a common femoral patch angioplasty requiring reoperation.
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spelling doaj.art-6e56fb45abde497a9fa64e8520d0f4aa2023-07-04T05:12:09ZengElsevierAnnals of Vascular Surgery - Brief Reports and Innovations2772-68782023-06-0132100192α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardiumAndrew Hawkins0Jeffrey M Wilson1Robert B. Hawkins2Christopher Moskaluk3Rung Chi Li4Margaret Tracci5Department of Surgery, Division of Vascular and Endovascular Surgery, University of Virginia, Charlottesville, VA 22908, United StatesDepartment of Allergy and Immunology, Charlottesville, VA, United StatesDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, MI, United StatesDepartment of Pathology, University of Virginia, Charlottesville, VA, United StatesDivision of Allergy and Immunology, Northern Light Health, Bangor, ME, United StatesDepartment of Surgery, Division of Vascular and Endovascular Surgery, University of Virginia, Charlottesville, VA 22908, United States; Corresponding author.α-Gal syndrome (AGS) is an allergy to meat and other products derived from non-primate mammals resulting from development of IgE antibodies against the oligosaccharide galactose-α,1,3-galactose (α-Gal). Sensitivity to α-Gal is linked to tick bites, particularly bites from Amblyomma americanum (lone star tick). Recent studies demonstrate early failure of bioprosthetic valves in the setting of chronic inflammation following exposure to animal-derived surgical implants. We report a case of AGS associated with restenosis of prior bovine pericardium used for a common femoral patch angioplasty requiring reoperation.http://www.sciencedirect.com/science/article/pii/S277268782300034Xα-Gal syndromeChronic inflammationCritical limb ischemiaBovine patch angioplastyIgE
spellingShingle Andrew Hawkins
Jeffrey M Wilson
Robert B. Hawkins
Christopher Moskaluk
Rung Chi Li
Margaret Tracci
α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
Annals of Vascular Surgery - Brief Reports and Innovations
α-Gal syndrome
Chronic inflammation
Critical limb ischemia
Bovine patch angioplasty
IgE
title α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
title_full α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
title_fullStr α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
title_full_unstemmed α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
title_short α-Gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
title_sort α gal as a cause for recurrent femoral artery stenosis after patch angioplasty with bovine pericardium
topic α-Gal syndrome
Chronic inflammation
Critical limb ischemia
Bovine patch angioplasty
IgE
url http://www.sciencedirect.com/science/article/pii/S277268782300034X
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