Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation
This study aimed to optimize velocity-selective magnetic resonance angiography (VS-MRA) protocols for whole-neck angiography and demonstrate its feasibility in healthy subjects with comparisons to clinical 3D time-of-flight (TOF) angiography. To help optimize VS-MRA protocols, 2D phase-contrast (PC)...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Tomography |
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| Online Access: | https://www.mdpi.com/2379-139X/9/1/6 |
| _version_ | 1797617990786613248 |
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| author | Chan Joo Park Seung Hong Choi Jaeseok Park Taehoon Shin |
| author_facet | Chan Joo Park Seung Hong Choi Jaeseok Park Taehoon Shin |
| author_sort | Chan Joo Park |
| collection | DOAJ |
| description | This study aimed to optimize velocity-selective magnetic resonance angiography (VS-MRA) protocols for whole-neck angiography and demonstrate its feasibility in healthy subjects with comparisons to clinical 3D time-of-flight (TOF) angiography. To help optimize VS-MRA protocols, 2D phase-contrast (PC) flow imaging and 3D B<sub>0</sub> and B<sub>1</sub> field mappings were performed on five healthy volunteers. Based on these measurements, a slab-selective (SS) inversion preparation was applied prior to a VS saturation preparation to further suppress venous blood, while the VS preparation pulse was designed with compensation for field offsets. VS-MRA and 3D TOF were performed on six healthy subjects, and relative contrast ratios (CRs) between artery and muscle signals were calculated for twenty arterial regions for comparisons. The pre-compensated VS pulse improved the visualization of the subclavian arteries and suppression of background tissues, which involved large B<sub>0</sub> and B<sub>1</sub> field errors. The combination of SS and VS preparations effectively suppressed venous blood. While the relative CR values were 0.78 ± 0.08 and 0.72 ± 0.10 for VS-MRA and 3D TOF, respectively, over the twenty segments, VS-MRA outperformed 3D TOF in visualizing arterial segments of a small size or with a horizontal orientation, such as subclavian, facial, and occipital arteries. The proposed neck VS-MRA with the field-error-compensated VS preparation combined with the SS preparation is feasible and superior to 3D TOF in visualizing small and/or horizontally oriented arterial segments. |
| first_indexed | 2024-03-11T08:03:50Z |
| format | Article |
| id | doaj.art-6e5a71cc14684d28b47abe451839c473 |
| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-11T08:03:50Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-6e5a71cc14684d28b47abe451839c4732023-11-16T23:36:21ZengMDPI AGTomography2379-13812379-139X2022-12-0191606910.3390/tomography9010006Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization PreparationChan Joo Park0Seung Hong Choi1Jaeseok Park2Taehoon Shin3Division of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul 03760, Republic of KoreaDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, Republic of KoreaDepartment of Biomedical Engineering, Sungkyunkwan University, Suwon 16419, Republic of KoreaDivision of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul 03760, Republic of KoreaThis study aimed to optimize velocity-selective magnetic resonance angiography (VS-MRA) protocols for whole-neck angiography and demonstrate its feasibility in healthy subjects with comparisons to clinical 3D time-of-flight (TOF) angiography. To help optimize VS-MRA protocols, 2D phase-contrast (PC) flow imaging and 3D B<sub>0</sub> and B<sub>1</sub> field mappings were performed on five healthy volunteers. Based on these measurements, a slab-selective (SS) inversion preparation was applied prior to a VS saturation preparation to further suppress venous blood, while the VS preparation pulse was designed with compensation for field offsets. VS-MRA and 3D TOF were performed on six healthy subjects, and relative contrast ratios (CRs) between artery and muscle signals were calculated for twenty arterial regions for comparisons. The pre-compensated VS pulse improved the visualization of the subclavian arteries and suppression of background tissues, which involved large B<sub>0</sub> and B<sub>1</sub> field errors. The combination of SS and VS preparations effectively suppressed venous blood. While the relative CR values were 0.78 ± 0.08 and 0.72 ± 0.10 for VS-MRA and 3D TOF, respectively, over the twenty segments, VS-MRA outperformed 3D TOF in visualizing arterial segments of a small size or with a horizontal orientation, such as subclavian, facial, and occipital arteries. The proposed neck VS-MRA with the field-error-compensated VS preparation combined with the SS preparation is feasible and superior to 3D TOF in visualizing small and/or horizontally oriented arterial segments.https://www.mdpi.com/2379-139X/9/1/6non-contrast-enhanced MRAneck angiographyvelocity-selective preparation pulse sequence |
| spellingShingle | Chan Joo Park Seung Hong Choi Jaeseok Park Taehoon Shin Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation Tomography non-contrast-enhanced MRA neck angiography velocity-selective preparation pulse sequence |
| title | Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation |
| title_full | Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation |
| title_fullStr | Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation |
| title_full_unstemmed | Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation |
| title_short | Whole-Neck Non-Contrast-Enhanced MR Angiography Using Velocity Selective Magnetization Preparation |
| title_sort | whole neck non contrast enhanced mr angiography using velocity selective magnetization preparation |
| topic | non-contrast-enhanced MRA neck angiography velocity-selective preparation pulse sequence |
| url | https://www.mdpi.com/2379-139X/9/1/6 |
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