Some new mathematical models of the fractional-order system of human immune against IAV infection

Fractional derivative operators of non-integer order can be utilized as a powerful tool to model nonlinear fractional differential equations. In this paper, we propose numerical solutions for simulating fractional-order derivative operators with the power-law and exponential-law kernels. We construc...

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Main Authors: H. M. Srivastava, Khaled M. Saad, J. F. Gómez-Aguilar, Abdulrhman A. Almadiy
Format: Article
Language:English
Published: AIMS Press 2020-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2020268?viewType=HTML
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author H. M. Srivastava
Khaled M. Saad
J. F. Gómez-Aguilar
Abdulrhman A. Almadiy
author_facet H. M. Srivastava
Khaled M. Saad
J. F. Gómez-Aguilar
Abdulrhman A. Almadiy
author_sort H. M. Srivastava
collection DOAJ
description Fractional derivative operators of non-integer order can be utilized as a powerful tool to model nonlinear fractional differential equations. In this paper, we propose numerical solutions for simulating fractional-order derivative operators with the power-law and exponential-law kernels. We construct the numerical schemes with the help the fundamental theorem of fractional calculus and the Lagrange polynomial interpolation. These schemes are applied to simulate the dynamical fractional-order model of the immune response (FMIR) to the uncomplicated influenza A virus (IAV) infection, which focuses on the control of the infection by the innate and adaptive immunity. Numerical results are then presented to show the applicability and efficiency on the FMIR.
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spelling doaj.art-6e5b9dfa675143c69144f8e2ef68045b2022-12-21T21:28:15ZengAIMS PressMathematical Biosciences and Engineering1551-00182020-07-011754942496910.3934/mbe.2020268Some new mathematical models of the fractional-order system of human immune against IAV infectionH. M. Srivastava0Khaled M. Saad1J. F. Gómez-Aguilar2Abdulrhman A. Almadiy 31. Department of Mathematics and Statistics, University of Victoria, Victoria, British Columbia V8W 3R4, Canada 2. Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, China 3. Department of Mathematics and Informatics, Azerbaijan University, 71 Jeyhun Hajibeyli Street, Baku AZ1007, Azerbaijan4. Department of Mathematics, College of Arts and Sciences, Najran University, Najran, Kingdom of Saudi Arabia 5. Department of Mathematics, Faculty of Applied Science, Taiz University, Taiz, Yemen6. CONACyT-Tecnológico Nacional de México/CENIDET, Interior Internado Palmira S/N, Col. Palmira, C. P. 62490, Cuernavaca Morelos, México7. Department of Biology, College of Arts and Sciences, Najran University, Najran, Kingdom of Saudi ArabiaFractional derivative operators of non-integer order can be utilized as a powerful tool to model nonlinear fractional differential equations. In this paper, we propose numerical solutions for simulating fractional-order derivative operators with the power-law and exponential-law kernels. We construct the numerical schemes with the help the fundamental theorem of fractional calculus and the Lagrange polynomial interpolation. These schemes are applied to simulate the dynamical fractional-order model of the immune response (FMIR) to the uncomplicated influenza A virus (IAV) infection, which focuses on the control of the infection by the innate and adaptive immunity. Numerical results are then presented to show the applicability and efficiency on the FMIR.https://www.aimspress.com/article/doi/10.3934/mbe.2020268?viewType=HTMLdynamical fractional-order model of immune response (fmir)lagrange polynomial interpolationinfluenza a virus (iav)
spellingShingle H. M. Srivastava
Khaled M. Saad
J. F. Gómez-Aguilar
Abdulrhman A. Almadiy
Some new mathematical models of the fractional-order system of human immune against IAV infection
Mathematical Biosciences and Engineering
dynamical fractional-order model of immune response (fmir)
lagrange polynomial interpolation
influenza a virus (iav)
title Some new mathematical models of the fractional-order system of human immune against IAV infection
title_full Some new mathematical models of the fractional-order system of human immune against IAV infection
title_fullStr Some new mathematical models of the fractional-order system of human immune against IAV infection
title_full_unstemmed Some new mathematical models of the fractional-order system of human immune against IAV infection
title_short Some new mathematical models of the fractional-order system of human immune against IAV infection
title_sort some new mathematical models of the fractional order system of human immune against iav infection
topic dynamical fractional-order model of immune response (fmir)
lagrange polynomial interpolation
influenza a virus (iav)
url https://www.aimspress.com/article/doi/10.3934/mbe.2020268?viewType=HTML
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