An In Vitro Study on Mitochondrial Compensatory Response Induced by Gliadin Peptides in Caco-2 Cells

An In Vitro Study on Mitochondrial Compensatory Response Induced by Gliadin Peptides in Caco-2 Cells

Dietary gliadin may show a broad spectrum of toxicity. The interplay between mitochondria and gliadin-induced oxidative stress has not been thoroughly examined in the intestinal epithelium. In this kinetic study, Caco-2 cells were exposed for 24 h to pepsin-trypsin-digested gliadin, alone or in comb...

Full description

Bibliographic Details
Main Authors: Antonella Orlando, Guglielmina Chimienti, Vito Pesce, Flavio Fracasso, Angela Maria Serena Lezza, Francesco Russo
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
Caco-2 cells
gliadin
gluten-related disorders
mitochondrial biogenesis
mtDNA
mtDNA damage
oxidative stress
PGC-1α
PrxIII
Online Access:https://www.mdpi.com/1422-0067/20/8/1862

Similar Items

Similar Items