Novel complex therapy of autumnal allergic blepharoconjuctivitis
Aim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizin...
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Ophthalmology Publishing Group
2014-10-01
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Series: | Oftalʹmologiâ |
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Online Access: | https://www.ophthalmojournal.com/opht/article/view/193 |
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author | S. V. Yanchenko A. V. Malyshev S. N. Sakhnov N. V. Fedotova O. Yu. Orlova I. V. Grishenko Z. A. Exuzyan |
author_facet | S. V. Yanchenko A. V. Malyshev S. N. Sakhnov N. V. Fedotova O. Yu. Orlova I. V. Grishenko Z. A. Exuzyan |
author_sort | S. V. Yanchenko |
collection | DOAJ |
description | Aim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizine 10 mg (1 tablet a day), and steroid drug (insufflations 2 times a day). Dry eye patients additionally received hyaluronic acid 1 mg / ml (instillations 2 times a day). 10 controls (20 eyes) were prescribed only the above-mentioned treatment. In 15 study group patients (30 eyes), Blepharogel 1 was applied on lid margins. Routine eye examination, clinical symptom assessment, Schirmer’s and Norn’s tests, xerosis meter and lissamine green staining evaluation, and anterior segment photography with computed morphometry were performed.Results. Compositae allergy was diagnosed in all patients. Dry eye due to tear film instability, lipid deficiency, and mucin deficiency and epitheliopathy were diagnosed in 55 %, 35.5 % and 28.3 %, respectively. In study group, the treatment significantly and rapidly reduced patient-reported symptoms and blepharoconjunctivitis signs as well as significantly improved tear stability, lipid deficiency, mucin deficiency, and epitheliopathy as compared with controls.Conclusion. Blepharogel 1 as a component of complex therapy increases the efficacy of autumnal allergic blepharoconjuctivitis treatment. |
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language | Russian |
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series | Oftalʹmologiâ |
spelling | doaj.art-6e611c4f4da24dedbd534341b57e70ed2023-03-13T09:08:36ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-10-01113747910.18008/1816-5095-2014-3-74-79193Novel complex therapy of autumnal allergic blepharoconjuctivitisS. V. Yanchenko0A. V. Malyshev1S. N. Sakhnov2N. V. Fedotova3O. Yu. Orlova4I. V. Grishenko5Z. A. Exuzyan6ГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России ГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России ГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России КФ ФГБУ «МНТК «Микрохирургия глаза» им. акад. С. Н . Фёдорова» Минздрава РоссииГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава РоссииAim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizine 10 mg (1 tablet a day), and steroid drug (insufflations 2 times a day). Dry eye patients additionally received hyaluronic acid 1 mg / ml (instillations 2 times a day). 10 controls (20 eyes) were prescribed only the above-mentioned treatment. In 15 study group patients (30 eyes), Blepharogel 1 was applied on lid margins. Routine eye examination, clinical symptom assessment, Schirmer’s and Norn’s tests, xerosis meter and lissamine green staining evaluation, and anterior segment photography with computed morphometry were performed.Results. Compositae allergy was diagnosed in all patients. Dry eye due to tear film instability, lipid deficiency, and mucin deficiency and epitheliopathy were diagnosed in 55 %, 35.5 % and 28.3 %, respectively. In study group, the treatment significantly and rapidly reduced patient-reported symptoms and blepharoconjunctivitis signs as well as significantly improved tear stability, lipid deficiency, mucin deficiency, and epitheliopathy as compared with controls.Conclusion. Blepharogel 1 as a component of complex therapy increases the efficacy of autumnal allergic blepharoconjuctivitis treatment.https://www.ophthalmojournal.com/opht/article/view/193аллергияполлинозный блефароконъюнктивитблефарогель-1 |
spellingShingle | S. V. Yanchenko A. V. Malyshev S. N. Sakhnov N. V. Fedotova O. Yu. Orlova I. V. Grishenko Z. A. Exuzyan Novel complex therapy of autumnal allergic blepharoconjuctivitis Oftalʹmologiâ аллергия поллинозный блефароконъюнктивит блефарогель-1 |
title | Novel complex therapy of autumnal allergic blepharoconjuctivitis |
title_full | Novel complex therapy of autumnal allergic blepharoconjuctivitis |
title_fullStr | Novel complex therapy of autumnal allergic blepharoconjuctivitis |
title_full_unstemmed | Novel complex therapy of autumnal allergic blepharoconjuctivitis |
title_short | Novel complex therapy of autumnal allergic blepharoconjuctivitis |
title_sort | novel complex therapy of autumnal allergic blepharoconjuctivitis |
topic | аллергия поллинозный блефароконъюнктивит блефарогель-1 |
url | https://www.ophthalmojournal.com/opht/article/view/193 |
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