Novel complex therapy of autumnal allergic blepharoconjuctivitis

Aim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizin...

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Main Authors: S. V. Yanchenko, A. V. Malyshev, S. N. Sakhnov, N. V. Fedotova, O. Yu. Orlova, I. V. Grishenko, Z. A. Exuzyan
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-10-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/193
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author S. V. Yanchenko
A. V. Malyshev
S. N. Sakhnov
N. V. Fedotova
O. Yu. Orlova
I. V. Grishenko
Z. A. Exuzyan
author_facet S. V. Yanchenko
A. V. Malyshev
S. N. Sakhnov
N. V. Fedotova
O. Yu. Orlova
I. V. Grishenko
Z. A. Exuzyan
author_sort S. V. Yanchenko
collection DOAJ
description Aim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizine 10 mg (1 tablet a day), and steroid drug (insufflations 2 times a day). Dry eye patients additionally received hyaluronic acid 1 mg / ml (instillations 2 times a day). 10 controls (20 eyes) were prescribed only the above-mentioned treatment. In 15 study group patients (30 eyes), Blepharogel 1 was applied on lid margins. Routine eye examination, clinical symptom assessment, Schirmer’s and Norn’s tests, xerosis meter and lissamine green staining evaluation, and anterior segment photography with computed morphometry were performed.Results. Compositae allergy was diagnosed in all patients. Dry eye due to tear film instability, lipid deficiency, and mucin deficiency and epitheliopathy were diagnosed in 55 %, 35.5 % and 28.3 %, respectively. In study group, the treatment significantly and rapidly reduced patient-reported symptoms and blepharoconjunctivitis signs as well as significantly improved tear stability, lipid deficiency, mucin deficiency, and epitheliopathy as compared with controls.Conclusion. Blepharogel 1 as a component of complex therapy increases the efficacy of autumnal allergic blepharoconjuctivitis treatment.
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spelling doaj.art-6e611c4f4da24dedbd534341b57e70ed2023-03-13T09:08:36ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-10-01113747910.18008/1816-5095-2014-3-74-79193Novel complex therapy of autumnal allergic blepharoconjuctivitisS. V. Yanchenko0A. V. Malyshev1S. N. Sakhnov2N. V. Fedotova3O. Yu. Orlova4I. V. Grishenko5Z. A. Exuzyan6ГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России ГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России ГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава России КФ ФГБУ «МНТК «Микрохирургия глаза» им. акад. С. Н . Фёдорова» Минздрава РоссииГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБУЗ «Краевая клиническая больница № 1 им. проф. С. В. Очаповского» Минздрава Краснодарского краяГБОУ ВПО «Кубанский государственный медицинский университет» Минздрава РоссииAim. To assess the effectivity of autumnal allergic blepharoconjuctivitis complex therapy.Methods. 25 autumnal allergic blepharoconjuctivitis patients (50 eyes) were examined before and after complex treatment that included olopatadine hydrochloride 1 mg / ml (instillations 2 times a day), cetirizine 10 mg (1 tablet a day), and steroid drug (insufflations 2 times a day). Dry eye patients additionally received hyaluronic acid 1 mg / ml (instillations 2 times a day). 10 controls (20 eyes) were prescribed only the above-mentioned treatment. In 15 study group patients (30 eyes), Blepharogel 1 was applied on lid margins. Routine eye examination, clinical symptom assessment, Schirmer’s and Norn’s tests, xerosis meter and lissamine green staining evaluation, and anterior segment photography with computed morphometry were performed.Results. Compositae allergy was diagnosed in all patients. Dry eye due to tear film instability, lipid deficiency, and mucin deficiency and epitheliopathy were diagnosed in 55 %, 35.5 % and 28.3 %, respectively. In study group, the treatment significantly and rapidly reduced patient-reported symptoms and blepharoconjunctivitis signs as well as significantly improved tear stability, lipid deficiency, mucin deficiency, and epitheliopathy as compared with controls.Conclusion. Blepharogel 1 as a component of complex therapy increases the efficacy of autumnal allergic blepharoconjuctivitis treatment.https://www.ophthalmojournal.com/opht/article/view/193аллергияполлинозный блефароконъюнктивитблефарогель-1
spellingShingle S. V. Yanchenko
A. V. Malyshev
S. N. Sakhnov
N. V. Fedotova
O. Yu. Orlova
I. V. Grishenko
Z. A. Exuzyan
Novel complex therapy of autumnal allergic blepharoconjuctivitis
Oftalʹmologiâ
аллергия
поллинозный блефароконъюнктивит
блефарогель-1
title Novel complex therapy of autumnal allergic blepharoconjuctivitis
title_full Novel complex therapy of autumnal allergic blepharoconjuctivitis
title_fullStr Novel complex therapy of autumnal allergic blepharoconjuctivitis
title_full_unstemmed Novel complex therapy of autumnal allergic blepharoconjuctivitis
title_short Novel complex therapy of autumnal allergic blepharoconjuctivitis
title_sort novel complex therapy of autumnal allergic blepharoconjuctivitis
topic аллергия
поллинозный блефароконъюнктивит
блефарогель-1
url https://www.ophthalmojournal.com/opht/article/view/193
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