A Role for Angiopoietin-2 in Organ-Specific Metastasis
Angiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the lung endothelium.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013-08-01
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| Series: | Cell Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713003963 |
| _version_ | 1818039054623571968 |
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| author | Nicolò Rigamonti Michele De Palma |
| author_facet | Nicolò Rigamonti Michele De Palma |
| author_sort | Nicolò Rigamonti |
| collection | DOAJ |
| description | Angiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the lung endothelium. |
| first_indexed | 2024-12-10T07:52:32Z |
| format | Article |
| id | doaj.art-6e6a45f7344f46ce9b6346cd20662e45 |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-12-10T07:52:32Z |
| publishDate | 2013-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-6e6a45f7344f46ce9b6346cd20662e452022-12-22T01:56:59ZengElsevierCell Reports2211-12472013-08-014462162310.1016/j.celrep.2013.07.034A Role for Angiopoietin-2 in Organ-Specific MetastasisNicolò Rigamonti0Michele De Palma1The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, SwitzerlandThe Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, SwitzerlandAngiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the lung endothelium.http://www.sciencedirect.com/science/article/pii/S2211124713003963 |
| spellingShingle | Nicolò Rigamonti Michele De Palma A Role for Angiopoietin-2 in Organ-Specific Metastasis Cell Reports |
| title | A Role for Angiopoietin-2 in Organ-Specific Metastasis |
| title_full | A Role for Angiopoietin-2 in Organ-Specific Metastasis |
| title_fullStr | A Role for Angiopoietin-2 in Organ-Specific Metastasis |
| title_full_unstemmed | A Role for Angiopoietin-2 in Organ-Specific Metastasis |
| title_short | A Role for Angiopoietin-2 in Organ-Specific Metastasis |
| title_sort | role for angiopoietin 2 in organ specific metastasis |
| url | http://www.sciencedirect.com/science/article/pii/S2211124713003963 |
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