A Role for Angiopoietin-2 in Organ-Specific Metastasis
Angiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the lung endothelium.
Main Authors: | Nicolò Rigamonti, Michele De Palma |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-08-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713003963 |
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