Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma
Aim. To evaluate 24-hour dynamics of the arterial stiffness main indicators in patients with bronchial asthma of various severity and control. Materials and methods. The study included 119 patients with bronchial asthma, who formed main groups: the first group 48 patients with mild and moderate a...
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2020-03-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/33891/pdf |
| _version_ | 1818561657679380480 |
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| author | N. A. Karoli O. T. Zarmanbetova A. P. Rebrov |
| author_facet | N. A. Karoli O. T. Zarmanbetova A. P. Rebrov |
| author_sort | N. A. Karoli |
| collection | DOAJ |
| description | Aim. To evaluate 24-hour dynamics of the arterial stiffness main indicators in patients with bronchial asthma of various severity and control.
Materials and methods. The study included 119 patients with bronchial asthma, who formed main groups: the first group 48 patients with mild and moderate asthma, the second 71 patients with severe asthma. All patients underwent the vascular stiffness parameters study using a multifunctional complex for the 24-hour monitoring and office measurements of blood pressure and vessels condition. At the same time vascular stiffness indicators were examined: PWVao pulse wave velocity in the aorta (m/s); Aix augmentation index (%); ASI the arterial stiffness index (mmHg).
Results. When comparing the 24-hour arterial stiffness dynamics indicators, changes were found in patients with severe asthma and non-control. Thus, a statistically significant increase in the pulse wave velocity in the aorta and augmentation index in second group compared to patients of the 1st group and control subjects. In patients with severe asthma Aix at night is significantly higher than daytime, which indicates an increase in arterial stiffness at night.
Conclusions. Patients with severe bronchial asthma have increased arterial stiffness in comparison with controls and mild and moderate asthma. Also, in patients with severe asthma arterial stiffness parameters were higher at night-time in comparison with daytime. |
| first_indexed | 2024-12-14T00:53:43Z |
| format | Article |
| id | doaj.art-6e6f36427a654794b7f2f576b77d6bf8 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-14T00:53:43Z |
| publishDate | 2020-03-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-6e6f36427a654794b7f2f576b77d6bf82022-12-21T23:23:41Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422020-03-01923303510.26442/00403660.2020.03.00043830578Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthmaN. A. Karoli0O. T. Zarmanbetova1A. P. Rebrov2Razumovsky Saratov State Medical UniversitySaratov City Polyclinic №6Razumovsky Saratov State Medical UniversityAim. To evaluate 24-hour dynamics of the arterial stiffness main indicators in patients with bronchial asthma of various severity and control. Materials and methods. The study included 119 patients with bronchial asthma, who formed main groups: the first group 48 patients with mild and moderate asthma, the second 71 patients with severe asthma. All patients underwent the vascular stiffness parameters study using a multifunctional complex for the 24-hour monitoring and office measurements of blood pressure and vessels condition. At the same time vascular stiffness indicators were examined: PWVao pulse wave velocity in the aorta (m/s); Aix augmentation index (%); ASI the arterial stiffness index (mmHg). Results. When comparing the 24-hour arterial stiffness dynamics indicators, changes were found in patients with severe asthma and non-control. Thus, a statistically significant increase in the pulse wave velocity in the aorta and augmentation index in second group compared to patients of the 1st group and control subjects. In patients with severe asthma Aix at night is significantly higher than daytime, which indicates an increase in arterial stiffness at night. Conclusions. Patients with severe bronchial asthma have increased arterial stiffness in comparison with controls and mild and moderate asthma. Also, in patients with severe asthma arterial stiffness parameters were higher at night-time in comparison with daytime.https://ter-arkhiv.ru/0040-3660/article/viewFile/33891/pdfbronchial asthmaarterial stiffnesspulse wave velocity аоrtiсaugmentation index |
| spellingShingle | N. A. Karoli O. T. Zarmanbetova A. P. Rebrov Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma Терапевтический архив bronchial asthma arterial stiffness pulse wave velocity аоrtiс augmentation index |
| title | Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma |
| title_full | Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma |
| title_fullStr | Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma |
| title_full_unstemmed | Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma |
| title_short | Clinical and diagnostical value of 24-hour arterial stiffness monitoring in patients with bronchial asthma |
| title_sort | clinical and diagnostical value of 24 hour arterial stiffness monitoring in patients with bronchial asthma |
| topic | bronchial asthma arterial stiffness pulse wave velocity аоrtiс augmentation index |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/33891/pdf |
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