Regulatory T-cells (Treg) in lymphoproliferative diseases
To purpose of the study was to research the level of regulatory T-lymphocytes (Treg) in lymphoproliferative diseases, and to evaluate their response to chemoradiotherapy. 71 studies of peripheral blood in patients with Hodgkin's lymphoma - HL (7), non-Hodgkin's lymphoma - nonHL (33) and ch...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Habib O.N.
2016-12-01
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| Series: | Современная онкология |
| Subjects: | |
| Online Access: | https://modernonco.orscience.ru/1815-1434/article/view/27115 |
| Summary: | To purpose of the study was to research the level of regulatory T-lymphocytes (Treg) in lymphoproliferative diseases, and to evaluate their response to chemoradiotherapy. 71 studies of peripheral blood in patients with Hodgkin's lymphoma - HL (7), non-Hodgkin's lymphoma - nonHL (33) and chronic lymphocytic leukemia - CLL (31) were carried out. The phenotype of Treg cells was determined by flow cytometry as a CD45+CD4+CD25+CD127-. The increased levels of regulatory T-cells in lymphoproliferative diseases (HL, NHL and CLL) are detected, as well as their relative resistance to the components of chemoradiation therapy. |
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| ISSN: | 1815-1434 1815-1442 |