Acetylcholine- and Sodium Hydrosulfide–Induced Endothelium-Dependent Relaxation and Hyperpolarization in Cerebral Vessels of Global Cerebral Ischemia–Reperfusion Rat

Acetylcholine- and Sodium Hydrosulfide–Induced Endothelium-Dependent Relaxation and Hyperpolarization in Cerebral Vessels of Global Cerebral Ischemia–Reperfusion Rat

Abstract.: We investigated the effects of endothelium-derived hyperpolarizing factor (EDHF) and the role of hydrogen sulphide (H2S) in the cerebral vasorelaxation induced by acetylcholine (ACh) in global cerebral ischemia–reperfusion (CIR) rats. CIR was induced by occlusion of bilateral carotid and...

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Bibliographic Details
Main Authors: Jun Han, Zhi-Wu Chen, Guo-Wei He
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319303615

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