Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (<it>FRG1</it>) expression during human myogenic differentiation

Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (<it>FRG1</it>) expression during human myogenic differentiation

<p>Abstract</p> <p>Background</p> <p>Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder associated with the partial deletion of integral numbers of 3.3 kb D4Z4 DNA repeats within the subtelomere of chromosome 4q. A number of ca...

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Bibliographic Details
Main Authors: Marozzi Anna, Meneveri Raffaella, Mora Marina, Brunelli Silvia, Cheli Stefania, Grasser Florian, Ramirez Gabriella, Bodega Beatrice, Mueller Stefan, Battaglioli Elena, Ginelli Enrico
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/7/41

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