Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer

Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer

Prostate cancer is an androgen-driven tumor. Different prostate cancer therapies consequently focus on blocking the androgen receptor pathway. Clinical studies reported tumor resistance mechanisms by reactivating and bypassing the androgen pathway. Preclinical models allowed the identification, conf...

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Bibliographic Details
Main Authors: Wout Devlies, Florian Handle, Gaëtan Devos, Steven Joniau, Frank Claessens
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
preclinical models
androgen receptor
prostate cancer
hormone treatment
ARSI
ARTA
Online Access:https://www.mdpi.com/2072-6694/13/4/915

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