Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019
Backgrounds: The human Parainfluenza and Influenza viruses are common causes of respiratory infections in humans. The main goals of this study was investigating the prevalence of these viruses in health centers of Mazandaran province and comparing the clinical manifestations. Materials and methods:...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences and Health Services
2019-08-01
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| Series: | Research in Molecular Medicine |
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| Online Access: | http://rmm.mazums.ac.ir/article-1-332-en.html |
| _version_ | 1819009101731987456 |
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| author | zeinab Daneshyar Hamid reza Goli Bahman Mirzaei Mehdi Rabie Mohammad reza Haghshenas |
| author_facet | zeinab Daneshyar Hamid reza Goli Bahman Mirzaei Mehdi Rabie Mohammad reza Haghshenas |
| author_sort | zeinab Daneshyar |
| collection | DOAJ |
| description | Backgrounds: The human Parainfluenza and Influenza viruses are common causes of respiratory infections in humans. The main goals of this study was investigating the prevalence of these viruses in health centers of Mazandaran province and comparing the clinical manifestations.
Materials and methods: The sample collection was done using Dacron swabs from the oropharynx of the patients, and the specimens were transferred to laboratory by Hanks medium. The Viral genomes were isolated by the extraction kits and the RT-PCR and Real time-PCR methods were used for detection of Influenza and Parainfluenza viruses’ prevalence in the specimens, respectively.
Results: Out of 100 samples, 5 (5%) specimens were positive for HPIV and 24 (24%) samples were detected as Influenza virus containing specimens. Among the all patients, 50 (50%) of them were female. No HPIV positive patients had croup. While any significant correlation was detected between personality characteristics (sex and age) and the infection with Parainfluenza viruses, but there was a significant relationship between sex and the detection of Influenza virus (p-value <0.05). Moreover, there was a significant relationship between some symptoms like pain and fever with the presence of Influenza virus and the symptoms such as fever and runny nose with the positive results for Parainfluenza in the clinical samples (p-value <0.05).
Conclusions: The results of the study revealed the high prevalence of Influenza disease in this region, indicating the necessity of an appropriate plan for the prevention and control using diagnostic tests like PCR. |
| first_indexed | 2024-12-21T00:51:01Z |
| format | Article |
| id | doaj.art-6e7eba75ceed45558a5a8c3b1e2df194 |
| institution | Directory Open Access Journal |
| issn | 2322-1348 2322-133X |
| language | English |
| last_indexed | 2024-12-21T00:51:01Z |
| publishDate | 2019-08-01 |
| publisher | Mazandaran University of Medical Sciences and Health Services |
| record_format | Article |
| series | Research in Molecular Medicine |
| spelling | doaj.art-6e7eba75ceed45558a5a8c3b1e2df1942022-12-21T19:21:24ZengMazandaran University of Medical Sciences and Health ServicesResearch in Molecular Medicine2322-13482322-133X2019-08-01732938Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019zeinab Daneshyar0Hamid reza Goli1Bahman Mirzaei2Mehdi Rabie3Mohammad reza Haghshenas4 Department of Microbiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Department of Microbiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Department of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Department of Microbiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Department of Microbiology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Backgrounds: The human Parainfluenza and Influenza viruses are common causes of respiratory infections in humans. The main goals of this study was investigating the prevalence of these viruses in health centers of Mazandaran province and comparing the clinical manifestations. Materials and methods: The sample collection was done using Dacron swabs from the oropharynx of the patients, and the specimens were transferred to laboratory by Hanks medium. The Viral genomes were isolated by the extraction kits and the RT-PCR and Real time-PCR methods were used for detection of Influenza and Parainfluenza viruses’ prevalence in the specimens, respectively. Results: Out of 100 samples, 5 (5%) specimens were positive for HPIV and 24 (24%) samples were detected as Influenza virus containing specimens. Among the all patients, 50 (50%) of them were female. No HPIV positive patients had croup. While any significant correlation was detected between personality characteristics (sex and age) and the infection with Parainfluenza viruses, but there was a significant relationship between sex and the detection of Influenza virus (p-value <0.05). Moreover, there was a significant relationship between some symptoms like pain and fever with the presence of Influenza virus and the symptoms such as fever and runny nose with the positive results for Parainfluenza in the clinical samples (p-value <0.05). Conclusions: The results of the study revealed the high prevalence of Influenza disease in this region, indicating the necessity of an appropriate plan for the prevention and control using diagnostic tests like PCR.http://rmm.mazums.ac.ir/article-1-332-en.htmlinfluenzahpivreal time-pcrrespiratory infection |
| spellingShingle | zeinab Daneshyar Hamid reza Goli Bahman Mirzaei Mehdi Rabie Mohammad reza Haghshenas Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 Research in Molecular Medicine influenza hpiv real time-pcr respiratory infection |
| title | Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 |
| title_full | Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 |
| title_fullStr | Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 |
| title_full_unstemmed | Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 |
| title_short | Prevalence and clinical symptoms of Human Parainfluenza and Influenza infections in patients admitted to Mazandaran province health centers, 2019 |
| title_sort | prevalence and clinical symptoms of human parainfluenza and influenza infections in patients admitted to mazandaran province health centers 2019 |
| topic | influenza hpiv real time-pcr respiratory infection |
| url | http://rmm.mazums.ac.ir/article-1-332-en.html |
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