Atg11 tethers Atg9 vesicles to initiate selective autophagy.
Autophagy recycles cytoplasmic components by sequestering them in double membrane-surrounded autophagosomes. The two proteins Atg11 and Atg17 are scaffolding components of the Atg1 kinase complex. Atg17 recruits and tethers Atg9-donor vesicles, and the corresponding Atg1 kinase complex induces the f...
Main Authors: | Nena Matscheko, Peter Mayrhofer, Yijian Rao, Viola Beier, Thomas Wollert |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-07-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000377 |
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