One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study

BACKGROUND: Cardiovascular diseases (CVDs) are one of the main concerns of health care systems. The aim of this study was to investigate the most important prognostic factors of heart failure (HF) and their survival outcomes in patients in Birjand, East of Iran.METHODS: A total of 194 systolic HF pa...

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Main Authors: Mahdi Abdollahi-Karizno, Neda Partovi, Vahid Noferesti, Naeem Ravanbakhsh, Toba Kazemi, Saeede Khosravi-Bizhaem
Format: Article
Language:English
Published: Vesnu Publications 2021-05-01
Series:ARYA Atherosclerosis
Subjects:
Online Access:https://arya.mui.ac.ir/article_10779_4b122624087544f4f0f7cc0d6d345915.pdf
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author Mahdi Abdollahi-Karizno
Neda Partovi
Vahid Noferesti
Naeem Ravanbakhsh
Toba Kazemi
Saeede Khosravi-Bizhaem
author_facet Mahdi Abdollahi-Karizno
Neda Partovi
Vahid Noferesti
Naeem Ravanbakhsh
Toba Kazemi
Saeede Khosravi-Bizhaem
author_sort Mahdi Abdollahi-Karizno
collection DOAJ
description BACKGROUND: Cardiovascular diseases (CVDs) are one of the main concerns of health care systems. The aim of this study was to investigate the most important prognostic factors of heart failure (HF) and their survival outcomes in patients in Birjand, East of Iran.METHODS: A total of 194 systolic HF patients hospitalized in Birjand Valiasr hospital were followed up for 12 months in 2016, and those with reduced left ventricle ejection fraction (LVEF < 50%) were included in this study. Kaplan-Meier and Cox proportional hazard analysis were used to determine the association of each factor with events.RESULTS: The mean age of patients was 68.23 ± 13.40 (27-95) years, and 57.2% (111 out of 194) were women. Mean survival time was 294.7 ± 9.924 days. Pervious history of myocardial infarction (MI) [2.141 (1.101-4.161)] increased the risk of cardiovascular hospitalization. Elevated blood levels of potassium [2.264 (1.438-3.564)] was found to be a risk factor for all-cause and cardiovascular mortality. Moreover, there was a reverse relationship between body height [0.942 (0.888-0.999)] and cardiovascular death. Patients with opium addiction [4.049 (1.310-12.516)] are at a higher risk of cardiovascular mortality. Lower levels of LDL-C [0.977 (0.960-0.996)] and living in rural areas [3.052 (1.039-8.964)] increased all-cause mortality levels. Lack of pervious history of chronic obstructive pulmonary disease (COPD) decreased cardiovascular hospitalization [0.265 (0.062-1.122)].CONCLUSION: In our study, serum potassium, LDL-C, and uric acid levels in patients with HF were identified as prognostic factors. The height of patients, which can be an indicator of the functional state of their respiratory system, and the history of COPD were also recognized as prognostic factors. Opium use and rural living were identified as social factors influencing patients' prognosis.
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spelling doaj.art-6e844da9a7e34eaf90da02bff472cc602023-03-11T12:59:30ZengVesnu PublicationsARYA Atherosclerosis1735-39552251-66382021-05-01171214910.22122/arya.v17i0.214910779One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center studyMahdi Abdollahi-Karizno0Neda Partovi1Vahid Noferesti2Naeem Ravanbakhsh3Toba Kazemi4Saeede Khosravi-Bizhaem5Medical Student, Student Research Committee, Birjand University of Medical Sciences, Birjand, IranAssistant Professor, Cardiovascular Diseases Research Center AND Department of Cardiology, School of Medicine, Birjand University of Medical Sciences, Birjand, IranMedical Student, Student Research Committee, Birjand University of Medical Sciences, Birjand, IranGeneral Practitioners, Student Research Committee, Birjand University of Medical Sciences, Birjand, IranProfessor, Razi Clinical Research Development Unit (RCRDU) AND Department of Cardiology, Cardiovascular Diseases Research Center, School of Medicine, Birjand University of Medical Sciences, Birjand, IranCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, IranBACKGROUND: Cardiovascular diseases (CVDs) are one of the main concerns of health care systems. The aim of this study was to investigate the most important prognostic factors of heart failure (HF) and their survival outcomes in patients in Birjand, East of Iran.METHODS: A total of 194 systolic HF patients hospitalized in Birjand Valiasr hospital were followed up for 12 months in 2016, and those with reduced left ventricle ejection fraction (LVEF < 50%) were included in this study. Kaplan-Meier and Cox proportional hazard analysis were used to determine the association of each factor with events.RESULTS: The mean age of patients was 68.23 ± 13.40 (27-95) years, and 57.2% (111 out of 194) were women. Mean survival time was 294.7 ± 9.924 days. Pervious history of myocardial infarction (MI) [2.141 (1.101-4.161)] increased the risk of cardiovascular hospitalization. Elevated blood levels of potassium [2.264 (1.438-3.564)] was found to be a risk factor for all-cause and cardiovascular mortality. Moreover, there was a reverse relationship between body height [0.942 (0.888-0.999)] and cardiovascular death. Patients with opium addiction [4.049 (1.310-12.516)] are at a higher risk of cardiovascular mortality. Lower levels of LDL-C [0.977 (0.960-0.996)] and living in rural areas [3.052 (1.039-8.964)] increased all-cause mortality levels. Lack of pervious history of chronic obstructive pulmonary disease (COPD) decreased cardiovascular hospitalization [0.265 (0.062-1.122)].CONCLUSION: In our study, serum potassium, LDL-C, and uric acid levels in patients with HF were identified as prognostic factors. The height of patients, which can be an indicator of the functional state of their respiratory system, and the history of COPD were also recognized as prognostic factors. Opium use and rural living were identified as social factors influencing patients' prognosis.https://arya.mui.ac.ir/article_10779_4b122624087544f4f0f7cc0d6d345915.pdfsystolic heart failureprognostic factorsfollow-up study
spellingShingle Mahdi Abdollahi-Karizno
Neda Partovi
Vahid Noferesti
Naeem Ravanbakhsh
Toba Kazemi
Saeede Khosravi-Bizhaem
One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
ARYA Atherosclerosis
systolic heart failure
prognostic factors
follow-up study
title One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
title_full One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
title_fullStr One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
title_full_unstemmed One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
title_short One-year survival cohort of patients with reduced ejection fraction heart failure in Iranian population: A single center study
title_sort one year survival cohort of patients with reduced ejection fraction heart failure in iranian population a single center study
topic systolic heart failure
prognostic factors
follow-up study
url https://arya.mui.ac.ir/article_10779_4b122624087544f4f0f7cc0d6d345915.pdf
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