Identification, biogenesis, function, and mechanism of action of circular RNAs in plants
Circular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique functions that are ubiquitously expressed in all eukaryotes. The biogenesis of circRNAs is regulated by specific cis-acting elements and trans-acting factors in humans and animals. circRNAs mainly exert their b...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
|
| Series: | Plant Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590346222002620 |
| _version_ | 1828067465020571648 |
|---|---|
| author | Ruiqi Liu Yu Ma Tao Guo Guanglin Li |
| author_facet | Ruiqi Liu Yu Ma Tao Guo Guanglin Li |
| author_sort | Ruiqi Liu |
| collection | DOAJ |
| description | Circular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique functions that are ubiquitously expressed in all eukaryotes. The biogenesis of circRNAs is regulated by specific cis-acting elements and trans-acting factors in humans and animals. circRNAs mainly exert their biological functions by acting as microRNA sponges, forming R-loops, interacting with RNA-binding proteins, or being translated into polypeptides or proteins in human and animal cells. Genome-wide identification of circRNAs has been performed in multiple plant species, and the results suggest that circRNAs are abundant and ubiquitously expressed in plants. There is emerging compelling evidence to suggest that circRNAs play essential roles during plant growth and development as well as in the responses to biotic and abiotic stress. However, compared with recent advances in human and animal systems, the roles of most circRNAs in plants are unclear at present. Here we review the identification, biogenesis, function, and mechanism of action of plant circRNAs, which will provide a fundamental understanding of the characteristics and complexity of circRNAs in plants. |
| first_indexed | 2024-04-10T23:45:54Z |
| format | Article |
| id | doaj.art-6e84dda61c9c4570b37dc72f75ec07f0 |
| institution | Directory Open Access Journal |
| issn | 2590-3462 |
| language | English |
| last_indexed | 2024-04-10T23:45:54Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Plant Communications |
| spelling | doaj.art-6e84dda61c9c4570b37dc72f75ec07f02023-01-11T04:30:08ZengElsevierPlant Communications2590-34622023-01-0141100430Identification, biogenesis, function, and mechanism of action of circular RNAs in plantsRuiqi Liu0Yu Ma1Tao Guo2Guanglin Li3Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi 710119, ChinaKey Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi 710119, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas and Institute of Future Agriculture, Northwest A&F University, Yangling, Shaanxi 712100, China; Corresponding authorKey Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi’an, Shaanxi 710119, China; Corresponding authorCircular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique functions that are ubiquitously expressed in all eukaryotes. The biogenesis of circRNAs is regulated by specific cis-acting elements and trans-acting factors in humans and animals. circRNAs mainly exert their biological functions by acting as microRNA sponges, forming R-loops, interacting with RNA-binding proteins, or being translated into polypeptides or proteins in human and animal cells. Genome-wide identification of circRNAs has been performed in multiple plant species, and the results suggest that circRNAs are abundant and ubiquitously expressed in plants. There is emerging compelling evidence to suggest that circRNAs play essential roles during plant growth and development as well as in the responses to biotic and abiotic stress. However, compared with recent advances in human and animal systems, the roles of most circRNAs in plants are unclear at present. Here we review the identification, biogenesis, function, and mechanism of action of plant circRNAs, which will provide a fundamental understanding of the characteristics and complexity of circRNAs in plants.http://www.sciencedirect.com/science/article/pii/S2590346222002620plant circRNAidentificationbiogenesisfunctionmechanism |
| spellingShingle | Ruiqi Liu Yu Ma Tao Guo Guanglin Li Identification, biogenesis, function, and mechanism of action of circular RNAs in plants Plant Communications plant circRNA identification biogenesis function mechanism |
| title | Identification, biogenesis, function, and mechanism of action of circular RNAs in plants |
| title_full | Identification, biogenesis, function, and mechanism of action of circular RNAs in plants |
| title_fullStr | Identification, biogenesis, function, and mechanism of action of circular RNAs in plants |
| title_full_unstemmed | Identification, biogenesis, function, and mechanism of action of circular RNAs in plants |
| title_short | Identification, biogenesis, function, and mechanism of action of circular RNAs in plants |
| title_sort | identification biogenesis function and mechanism of action of circular rnas in plants |
| topic | plant circRNA identification biogenesis function mechanism |
| url | http://www.sciencedirect.com/science/article/pii/S2590346222002620 |
| work_keys_str_mv | AT ruiqiliu identificationbiogenesisfunctionandmechanismofactionofcircularrnasinplants AT yuma identificationbiogenesisfunctionandmechanismofactionofcircularrnasinplants AT taoguo identificationbiogenesisfunctionandmechanismofactionofcircularrnasinplants AT guanglinli identificationbiogenesisfunctionandmechanismofactionofcircularrnasinplants |