Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States
Background: Atrial flutter (AFL) is a common arrhythmia associated with significant morbidity, yet the incremental burden of this condition has not been well documented. Objective: Using real-world data, we sought to evaluate the healthcare use and cost burden of incident AFL in the United States Me...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Heart Rhythm O2 |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666501823000909 |
| _version_ | 1797798604744687616 |
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| author | Abhishek Deshmukh, MD Maximiliano Iglesias, BE, MBA Rahul Khanna, MBA, PhD Tara Beaulieu, MIPH, PhD |
| author_facet | Abhishek Deshmukh, MD Maximiliano Iglesias, BE, MBA Rahul Khanna, MBA, PhD Tara Beaulieu, MIPH, PhD |
| author_sort | Abhishek Deshmukh, MD |
| collection | DOAJ |
| description | Background: Atrial flutter (AFL) is a common arrhythmia associated with significant morbidity, yet the incremental burden of this condition has not been well documented. Objective: Using real-world data, we sought to evaluate the healthcare use and cost burden of incident AFL in the United States Methods: From 2017 to 2020, persons with an incident diagnosis of AFL were identified through Optum Clinformatics, a nationally representative administrative claims database of commercially insured individuals in the United States. We constructed 2 cohorts (AFL patient; non-AFL comparator) and used a matching weights method to balance covariates between cohorts. Using logistic regression and general linear models, 12-month all-cause and cardiovascular (CV)-related health care use (inpatient, outpatient, emergency room [ER] visits, and other) as well as medical expenditures were compared between the matched cohorts. Results: The matching weight sample sizes were 13,270 for AFL and 13,683 for the non-AFL cohorts. In the AFL cohort, ∼71% were at least 70 years of age, 62% identified as male, and 78% identified as White. The AFL cohort had significantly higher health care use, including all-cause (relative risk [RR] 1.14; 95% confidence interval [CI] 1.11–1.18) and CV-related ER visits (RR 1.60; 95% CI 1.52–1.70) compared with the non-AFL cohort. Mean total health care costs (per patient annually) were almost $21,783 (95% CI $18,967–$24,599) higher among patients with AFL compared to those without AFL ($71,201 vs $49,418, respectively; P <.001). Conclusion: Amidst the backdrop of an aging population, findings from this study draw attention to the importance of timely and adequate treatment of AFL. |
| first_indexed | 2024-03-13T04:06:20Z |
| format | Article |
| id | doaj.art-6e869d5115344716b6d98c158c91e30d |
| institution | Directory Open Access Journal |
| issn | 2666-5018 |
| language | English |
| last_indexed | 2024-03-13T04:06:20Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heart Rhythm O2 |
| spelling | doaj.art-6e869d5115344716b6d98c158c91e30d2023-06-21T07:00:33ZengElsevierHeart Rhythm O22666-50182023-06-0146367373Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United StatesAbhishek Deshmukh, MD0Maximiliano Iglesias, BE, MBA1Rahul Khanna, MBA, PhD2Tara Beaulieu, MIPH, PhD3Division of Cardiovascular Disease, Mayo Clinic, Rochester, MinnesotaJohnson & Johnson Medical Devices, Franchise Health Economics and Market Access, Irvine, CaliforniaMedTech Epidemiology and Real-World Data Sciences, Johnson and Johnson, New Brunswick, New Jersey; Address reprint requests and correspondence: Dr Rahul Khanna, MedTech Epidemiology and Real-World Data Sciences Johnson and Johnson, 410 George St, New Brunswick, NJ 08901.MedTech Epidemiology and Real-World Data Sciences, Johnson and Johnson, New Brunswick, New JerseyBackground: Atrial flutter (AFL) is a common arrhythmia associated with significant morbidity, yet the incremental burden of this condition has not been well documented. Objective: Using real-world data, we sought to evaluate the healthcare use and cost burden of incident AFL in the United States Methods: From 2017 to 2020, persons with an incident diagnosis of AFL were identified through Optum Clinformatics, a nationally representative administrative claims database of commercially insured individuals in the United States. We constructed 2 cohorts (AFL patient; non-AFL comparator) and used a matching weights method to balance covariates between cohorts. Using logistic regression and general linear models, 12-month all-cause and cardiovascular (CV)-related health care use (inpatient, outpatient, emergency room [ER] visits, and other) as well as medical expenditures were compared between the matched cohorts. Results: The matching weight sample sizes were 13,270 for AFL and 13,683 for the non-AFL cohorts. In the AFL cohort, ∼71% were at least 70 years of age, 62% identified as male, and 78% identified as White. The AFL cohort had significantly higher health care use, including all-cause (relative risk [RR] 1.14; 95% confidence interval [CI] 1.11–1.18) and CV-related ER visits (RR 1.60; 95% CI 1.52–1.70) compared with the non-AFL cohort. Mean total health care costs (per patient annually) were almost $21,783 (95% CI $18,967–$24,599) higher among patients with AFL compared to those without AFL ($71,201 vs $49,418, respectively; P <.001). Conclusion: Amidst the backdrop of an aging population, findings from this study draw attention to the importance of timely and adequate treatment of AFL.http://www.sciencedirect.com/science/article/pii/S2666501823000909ArrhythmiaAtrial flutterCost burdenHealth care use burdenUnited States |
| spellingShingle | Abhishek Deshmukh, MD Maximiliano Iglesias, BE, MBA Rahul Khanna, MBA, PhD Tara Beaulieu, MIPH, PhD Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States Heart Rhythm O2 Arrhythmia Atrial flutter Cost burden Health care use burden United States |
| title | Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States |
| title_full | Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States |
| title_fullStr | Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States |
| title_full_unstemmed | Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States |
| title_short | Atrial flutter-related health care use and costs: An analysis of a nationally representative administrative claims database in the United States |
| title_sort | atrial flutter related health care use and costs an analysis of a nationally representative administrative claims database in the united states |
| topic | Arrhythmia Atrial flutter Cost burden Health care use burden United States |
| url | http://www.sciencedirect.com/science/article/pii/S2666501823000909 |
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