Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?

A variety of infectious agents can cause secondary immunodeficient states. We herein present a one-year-old patient, admitted to the hospital with severe lymphopenia, who was subsequently diagnosed as tuberculosis. After the antituberculosis (anti TB) therapy was started, the clinical conditi...

Full description

Bibliographic Details
Main Authors: E N Gönç, S Ozen, A Göçmen, Y Zafer, I Tezcan
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2000-01-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/3103
_version_ 1826543670418997248
author E N Gönç
S Ozen
A Göçmen
Y Zafer
I Tezcan
author_facet E N Gönç
S Ozen
A Göçmen
Y Zafer
I Tezcan
author_sort E N Gönç
collection DOAJ
description A variety of infectious agents can cause secondary immunodeficient states. We herein present a one-year-old patient, admitted to the hospital with severe lymphopenia, who was subsequently diagnosed as tuberculosis. After the antituberculosis (anti TB) therapy was started, the clinical condition and the immunologic findings of the patient improved. We have thus concluded that the transient lymphopenia of the patient was due to Mycobacterium tuberculosis. We suggest that immunodeficiency should be investigated more often in children with tuberculosis and that further studies will shed light on the pathogenesis of this aspect of the disease.
first_indexed 2025-03-14T04:49:46Z
format Article
id doaj.art-6e87d87ce5e1497f95ff2d8506c8bce1
institution Directory Open Access Journal
issn 0041-4301
2791-6421
language English
last_indexed 2025-03-14T04:49:46Z
publishDate 2000-01-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj.art-6e87d87ce5e1497f95ff2d8506c8bce12025-03-07T19:43:54ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212000-01-01421Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?E N Gönç0S OzenA GöçmenY ZaferI TezcanDepartment of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. A variety of infectious agents can cause secondary immunodeficient states. We herein present a one-year-old patient, admitted to the hospital with severe lymphopenia, who was subsequently diagnosed as tuberculosis. After the antituberculosis (anti TB) therapy was started, the clinical condition and the immunologic findings of the patient improved. We have thus concluded that the transient lymphopenia of the patient was due to Mycobacterium tuberculosis. We suggest that immunodeficiency should be investigated more often in children with tuberculosis and that further studies will shed light on the pathogenesis of this aspect of the disease. https://turkjpediatr.org/article/view/3103
spellingShingle E N Gönç
S Ozen
A Göçmen
Y Zafer
I Tezcan
Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
The Turkish Journal of Pediatrics
title Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
title_full Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
title_fullStr Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
title_full_unstemmed Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
title_short Severe lymphopenia in tuberculosis. A mere coincidence or a significant association?
title_sort severe lymphopenia in tuberculosis a mere coincidence or a significant association
url https://turkjpediatr.org/article/view/3103
work_keys_str_mv AT engonc severelymphopeniaintuberculosisamerecoincidenceorasignificantassociation
AT sozen severelymphopeniaintuberculosisamerecoincidenceorasignificantassociation
AT agocmen severelymphopeniaintuberculosisamerecoincidenceorasignificantassociation
AT yzafer severelymphopeniaintuberculosisamerecoincidenceorasignificantassociation
AT itezcan severelymphopeniaintuberculosisamerecoincidenceorasignificantassociation