Effect of Sow Intestinal Flora on the Formation of Endometritis
Endometritis is the main cause of decreased reproductive performance of sows, while one of the most important factors in the etiology of sow endometritis is an aberration of birth canal microbiota. Therefore, people began to pay attention to the microbiota structure and composition of the birth cana...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.663956/full |
| _version_ | 1818918658202664960 |
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| author | Ling Zhang Linkang Wang Yimin Dai Tianyu Tao Jingqi Wang Yunzheng Wu Xiu Zeng Jinhua Zhang |
| author_facet | Ling Zhang Linkang Wang Yimin Dai Tianyu Tao Jingqi Wang Yunzheng Wu Xiu Zeng Jinhua Zhang |
| author_sort | Ling Zhang |
| collection | DOAJ |
| description | Endometritis is the main cause of decreased reproductive performance of sows, while one of the most important factors in the etiology of sow endometritis is an aberration of birth canal microbiota. Therefore, people began to pay attention to the microbiota structure and composition of the birth canal of sows with endometritis. Interestingly, we found that the risk of endometritis was increased in the sows with constipation in clinical practice, which may imply that the intestinal flora is related to the occurrence of endometritis. Therefore, understanding the relationship between birth canal microbiota and intestinal microbiota of the host has become exceptionally crucial. In this study, the microbiota of birth canal secretions and fresh feces of four healthy and four endometritis sows were analyzed via sequencing the V3 + V4 region of bacterial 16S ribosomal (rDNA) gene. The results showed a significant difference between endometritis and healthy sows birth canal flora in composition and abundance. Firmicutes (74.36%) and Proteobacteria were the most dominant phyla in birth canal microbiota of healthy sows. However, the majority of beneficial bacteria that belonging to Firmicutes phylum (e.g., Lactobacillus and Enterococcus) declined in endometritis sow. The abundance of Porphyromonas, Clostridium sensu stricto 1, Streptococcus, Fusobacterium, Actinobacillus, and Bacteroides increased significantly in the birth canal microbiota of endometritis sows. Escherichia–Shigella and Bacteroides were the common genera in the birth canal and intestinal flora of endometritis sows. The abundance of Escherichia–Shigella and Bacteroides in the intestines of sows suffering from endometritis were significantly increased than the intestinal microbiota of the healthy sows. We speculated that some intestinal bacteria (such as Escherichia–Shigella and Bacteroides) might be bound up with the onset of sow endometritis based on intestinal microbiota analysis in sows with endometritis and healthy sows. The above results can supply a theoretical basis to research the pathogenesis of endometritis and help others understand the relationship with the microbiota of sow's birth canal and gut. |
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| format | Article |
| id | doaj.art-6e8b46a9c4a045289a1e22ea897b5161 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-20T00:53:27Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-6e8b46a9c4a045289a1e22ea897b51612022-12-21T19:59:10ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-06-01810.3389/fvets.2021.663956663956Effect of Sow Intestinal Flora on the Formation of EndometritisLing ZhangLinkang WangYimin DaiTianyu TaoJingqi WangYunzheng WuXiu ZengJinhua ZhangEndometritis is the main cause of decreased reproductive performance of sows, while one of the most important factors in the etiology of sow endometritis is an aberration of birth canal microbiota. Therefore, people began to pay attention to the microbiota structure and composition of the birth canal of sows with endometritis. Interestingly, we found that the risk of endometritis was increased in the sows with constipation in clinical practice, which may imply that the intestinal flora is related to the occurrence of endometritis. Therefore, understanding the relationship between birth canal microbiota and intestinal microbiota of the host has become exceptionally crucial. In this study, the microbiota of birth canal secretions and fresh feces of four healthy and four endometritis sows were analyzed via sequencing the V3 + V4 region of bacterial 16S ribosomal (rDNA) gene. The results showed a significant difference between endometritis and healthy sows birth canal flora in composition and abundance. Firmicutes (74.36%) and Proteobacteria were the most dominant phyla in birth canal microbiota of healthy sows. However, the majority of beneficial bacteria that belonging to Firmicutes phylum (e.g., Lactobacillus and Enterococcus) declined in endometritis sow. The abundance of Porphyromonas, Clostridium sensu stricto 1, Streptococcus, Fusobacterium, Actinobacillus, and Bacteroides increased significantly in the birth canal microbiota of endometritis sows. Escherichia–Shigella and Bacteroides were the common genera in the birth canal and intestinal flora of endometritis sows. The abundance of Escherichia–Shigella and Bacteroides in the intestines of sows suffering from endometritis were significantly increased than the intestinal microbiota of the healthy sows. We speculated that some intestinal bacteria (such as Escherichia–Shigella and Bacteroides) might be bound up with the onset of sow endometritis based on intestinal microbiota analysis in sows with endometritis and healthy sows. The above results can supply a theoretical basis to research the pathogenesis of endometritis and help others understand the relationship with the microbiota of sow's birth canal and gut.https://www.frontiersin.org/articles/10.3389/fvets.2021.663956/fullsowendometritisbirth canalintestinal flora16S rDNA gene |
| spellingShingle | Ling Zhang Linkang Wang Yimin Dai Tianyu Tao Jingqi Wang Yunzheng Wu Xiu Zeng Jinhua Zhang Effect of Sow Intestinal Flora on the Formation of Endometritis Frontiers in Veterinary Science sow endometritis birth canal intestinal flora 16S rDNA gene |
| title | Effect of Sow Intestinal Flora on the Formation of Endometritis |
| title_full | Effect of Sow Intestinal Flora on the Formation of Endometritis |
| title_fullStr | Effect of Sow Intestinal Flora on the Formation of Endometritis |
| title_full_unstemmed | Effect of Sow Intestinal Flora on the Formation of Endometritis |
| title_short | Effect of Sow Intestinal Flora on the Formation of Endometritis |
| title_sort | effect of sow intestinal flora on the formation of endometritis |
| topic | sow endometritis birth canal intestinal flora 16S rDNA gene |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2021.663956/full |
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