Cytoglobin Attenuates Neuroinflammation in Lipopolysaccharide-Activated Primary Preoptic Area Cells via NF-κB Pathway Inhibition

Cytoglobin Attenuates Neuroinflammation in Lipopolysaccharide-Activated Primary Preoptic Area Cells via NF-κB Pathway Inhibition

Cytoglobin (Cygb) is a hexacoordinate protein, associated with the transport of oxygen, nitric oxide scavenging, tumor suppression and protection against oxidative stress and inflammation. This protein is expressed in brain areas including the preoptic area (POA) of the anterior hypothalamus, the re...

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Bibliographic Details
Main Authors: Bruna R. B. Gomes, Gabriela Luna S. de Sousa, Daniela Ott, Jolanta Murgott, Marcelo V. de Sousa, Paulo E. N. de Souza, Joachim Roth, Fabiane H. Veiga-Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cytoglobin
neuroinflammation
fever
preoptic area
primary culture
hypothalamus
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00307/full

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