Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease
Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of Veterinary Internal Medicine (ACVIM) uses clinical, echocardiographic, and radiographic criteria to diagnose the disease, but measurement of vertebral...
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| Format: | Article |
| Language: | English |
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Ss.Cyril and Methodius University, Skopje
2023-10-01
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| Series: | Macedonian Veterinary Review |
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| Online Access: | https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2023_0023 |
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| author | Gonul Remzi Hande Sağoğlu Murat Suzan |
| author_facet | Gonul Remzi Hande Sağoğlu Murat Suzan |
| author_sort | Gonul Remzi |
| collection | DOAJ |
| description | Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of Veterinary Internal Medicine (ACVIM) uses clinical, echocardiographic, and radiographic criteria to diagnose the disease, but measurement of vertebral left atrial size (VLAS) provides a simpler assessment. The aim of this study was to determine VLAS values in MMVD cases of CKCS and to investigate their clinical significance at different MMVD stages. Eighteen CKCS dogs of both sexes, different ages and weights, and different MMVD stages (6 at B1 stage, 6 at B2 stage, and 6 at C stage) were included in the study, as well as 6 healthy CKCS as control group A. We performed clinical, radiological, and echocardiographic examinations. VHS and VLAS values were significantly higher in the MMVD group than in the control group (p<0.001). VLAS showed high diagnostic accuracy in the detection of LA enlargement (area under the curve [AUC]: 0.98, cutoff ≥ 2.25, sensitivity: 88%, specificity: 100%, p<0.001). We also found high positive correlations between the VLAS and other values (LA /Ao, LVIDDn, and VHS) (r=0.88, r=0.88, and r=0.86, respectively) (p<0.001). It has been concluded that a VLAS value ≥2.25 can provide a meaningful diagnosis of left atrial enlargement in dogs with MMVD CKCS. |
| first_indexed | 2024-03-11T17:55:04Z |
| format | Article |
| id | doaj.art-6e8b826212eb423d9031a4582e5e03dd |
| institution | Directory Open Access Journal |
| issn | 1409-7621 1857-7415 |
| language | English |
| last_indexed | 2024-03-11T17:55:04Z |
| publishDate | 2023-10-01 |
| publisher | Ss.Cyril and Methodius University, Skopje |
| record_format | Article |
| series | Macedonian Veterinary Review |
| spelling | doaj.art-6e8b826212eb423d9031a4582e5e03dd2023-10-17T13:11:09ZengSs.Cyril and Methodius University, SkopjeMacedonian Veterinary Review1409-76211857-74152023-10-0146216517010.2478/macvetrev-2023-0023Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve diseaseGonul Remzi0https://orcid.org/0000-0001-9425-0964Hande Sağoğlu1https://orcid.org/0000-0002-4538-3960Murat Suzan2https://orcid.org/0000-0002-5853-2160Department of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University Cerrahpasa, Avcılar Yerleşkesi, Üniversite Mahallesi, 34320 Avcılar/İstanbul, TürkiyeDepartment of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University Cerrahpasa, Avcılar Yerleşkesi, Üniversite Mahallesi, 34320 Avcılar/İstanbul, TürkiyeDepartment of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University Cerrahpasa, Avcılar Yerleşkesi, Üniversite Mahallesi, 34320 Avcılar/İstanbul, TürkiyeMyxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of Veterinary Internal Medicine (ACVIM) uses clinical, echocardiographic, and radiographic criteria to diagnose the disease, but measurement of vertebral left atrial size (VLAS) provides a simpler assessment. The aim of this study was to determine VLAS values in MMVD cases of CKCS and to investigate their clinical significance at different MMVD stages. Eighteen CKCS dogs of both sexes, different ages and weights, and different MMVD stages (6 at B1 stage, 6 at B2 stage, and 6 at C stage) were included in the study, as well as 6 healthy CKCS as control group A. We performed clinical, radiological, and echocardiographic examinations. VHS and VLAS values were significantly higher in the MMVD group than in the control group (p<0.001). VLAS showed high diagnostic accuracy in the detection of LA enlargement (area under the curve [AUC]: 0.98, cutoff ≥ 2.25, sensitivity: 88%, specificity: 100%, p<0.001). We also found high positive correlations between the VLAS and other values (LA /Ao, LVIDDn, and VHS) (r=0.88, r=0.88, and r=0.86, respectively) (p<0.001). It has been concluded that a VLAS value ≥2.25 can provide a meaningful diagnosis of left atrial enlargement in dogs with MMVD CKCS.https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2023_0023left atrial sizecavaliermyxomatous mitral valve |
| spellingShingle | Gonul Remzi Hande Sağoğlu Murat Suzan Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease Macedonian Veterinary Review left atrial size cavalier myxomatous mitral valve |
| title | Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease |
| title_full | Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease |
| title_fullStr | Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease |
| title_full_unstemmed | Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease |
| title_short | Radiographic evaluation of left atrial size in Cavalier King Charles spaniel dogs with mitral valve disease |
| title_sort | radiographic evaluation of left atrial size in cavalier king charles spaniel dogs with mitral valve disease |
| topic | left atrial size cavalier myxomatous mitral valve |
| url | https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2023_0023 |
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