Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists

Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists

The mineralocorticoid receptor (MR) belongs to the steroid receptor subfamily of nuclear receptors. MR is a transcription factor key in regulating blood pressure and mineral homeostasis. In addition, it plays an important role in a broad range of biological and pathological conditions, greatly expan...

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Bibliographic Details
Main Authors: Felipe Luis Pérez-Gordillo, Natalia Serrano-Morillas, Luz Marina Acosta-García, María Teresa Aranda, Daniela Passeri, Roberto Pellicciari, María Jesús Pérez de Vega, Rosario González-Muñiz, Diego Alvarez de la Rosa, Mercedes Martín-Martínez
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
MR
nuclear receptor
NR3C2
aldosterone
DHP
antagonist
Online Access:https://www.mdpi.com/1422-0067/24/3/2439

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