Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum
Metabolic diseases during early lactation in dairy cows can be routinely diagnosed assessing key indicators in blood. The objectives of the present study were to characterize the impact of interindividual along with intraday variation on specific metabolites and to investigate the effect of the samp...
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| Format: | Article |
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Czech Academy of Agricultural Sciences
2013-08-01
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| Series: | Czech Journal of Animal Science |
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| Online Access: | https://cjas.agriculturejournals.cz/artkey/cjs-201308-0001_intraday-variation-of-metabolic-key-indicators-in-serum-of-dairy-cows-between-week-2-antepartum-and-week-12-pos.php |
| _version_ | 1797899190995517440 |
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| author | S. Wiedemann K. Horstmann M. Piechotta U. Meyer G. Flachowsky M. Kaske |
| author_facet | S. Wiedemann K. Horstmann M. Piechotta U. Meyer G. Flachowsky M. Kaske |
| author_sort | S. Wiedemann |
| collection | DOAJ |
| description | Metabolic diseases during early lactation in dairy cows can be routinely diagnosed assessing key indicators in blood. The objectives of the present study were to characterize the impact of interindividual along with intraday variation on specific metabolites and to investigate the effect of the sampling time point relative to calving. Serum samples of four high-yielding, clinically healthy, multiparous dairy cows (body weight 589 ± 27 kg) were obtained in 3-h intervals during 24-h intervals throughout the transition period and early lactation (week -2 antepartum (ap), weeks 1, 2, 3, 5, 7, and 12 postpartum (pp)). The lowest intraday variation (less than 15%) as indicated by relative coefficients of variation (CV) was found for glucose, cholesterol, and aspartate aminotransferase (AST). Intraday variation characterized by a CV between 15 and 30% was typical of urea, β-hydroxybutyrate (BHB), total bilirubin, and non-esterified fatty acids (NEFA). The highest intraday variation (CV > 30%) was assessed for insulin. Week relative to calving had significant influence on interindividual means of BHB, NEFA, insulin, and cholesterol in blood, but did not affect the interindividual variation of all parameters investigated. No significant intraday variation patterns were found. It is concluded that the considerable intraday variation of especially BHB and NEFA has to be taken into account in herd health monitoring for estimating the proportional outcome in respect to animals exceeding thresholds for specific metabolic key parameters. |
| first_indexed | 2024-04-10T08:26:08Z |
| format | Article |
| id | doaj.art-6e8d36d8f4df4fcc9c35279da527d487 |
| institution | Directory Open Access Journal |
| issn | 1212-1819 1805-9309 |
| language | English |
| last_indexed | 2024-04-10T08:26:08Z |
| publishDate | 2013-08-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Czech Journal of Animal Science |
| spelling | doaj.art-6e8d36d8f4df4fcc9c35279da527d4872023-02-23T03:33:06ZengCzech Academy of Agricultural SciencesCzech Journal of Animal Science1212-18191805-93092013-08-0158834335010.17221/6900-CJAScjs-201308-0001Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartumS. Wiedemann0K. Horstmann1M. Piechotta2U. Meyer3G. Flachowsky4M. Kaske5Institute of Animal Breeding and Husbandry, Christian-Albrechts-University Kiel, Kiel, GermanyClinic for Cattle, University of Veterinary Medicine, Hannover, GermanyClinic for Cattle, University of Veterinary Medicine, Hannover, GermanyInstitute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute of Animal Health, Braunschweig, GermanyInstitute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute of Animal Health, Braunschweig, GermanyClinic for Cattle, University of Veterinary Medicine, Hannover, GermanyMetabolic diseases during early lactation in dairy cows can be routinely diagnosed assessing key indicators in blood. The objectives of the present study were to characterize the impact of interindividual along with intraday variation on specific metabolites and to investigate the effect of the sampling time point relative to calving. Serum samples of four high-yielding, clinically healthy, multiparous dairy cows (body weight 589 ± 27 kg) were obtained in 3-h intervals during 24-h intervals throughout the transition period and early lactation (week -2 antepartum (ap), weeks 1, 2, 3, 5, 7, and 12 postpartum (pp)). The lowest intraday variation (less than 15%) as indicated by relative coefficients of variation (CV) was found for glucose, cholesterol, and aspartate aminotransferase (AST). Intraday variation characterized by a CV between 15 and 30% was typical of urea, β-hydroxybutyrate (BHB), total bilirubin, and non-esterified fatty acids (NEFA). The highest intraday variation (CV > 30%) was assessed for insulin. Week relative to calving had significant influence on interindividual means of BHB, NEFA, insulin, and cholesterol in blood, but did not affect the interindividual variation of all parameters investigated. No significant intraday variation patterns were found. It is concluded that the considerable intraday variation of especially BHB and NEFA has to be taken into account in herd health monitoring for estimating the proportional outcome in respect to animals exceeding thresholds for specific metabolic key parameters.https://cjas.agriculturejournals.cz/artkey/cjs-201308-0001_intraday-variation-of-metabolic-key-indicators-in-serum-of-dairy-cows-between-week-2-antepartum-and-week-12-pos.phpblood metaboliteslactationtwenty-four-hour pattern |
| spellingShingle | S. Wiedemann K. Horstmann M. Piechotta U. Meyer G. Flachowsky M. Kaske Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum Czech Journal of Animal Science blood metabolites lactation twenty-four-hour pattern |
| title | Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| title_full | Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| title_fullStr | Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| title_full_unstemmed | Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| title_short | Intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| title_sort | intraday variation of metabolic key indicators in serum of dairy cows between week 2 antepartum and week 12 postpartum |
| topic | blood metabolites lactation twenty-four-hour pattern |
| url | https://cjas.agriculturejournals.cz/artkey/cjs-201308-0001_intraday-variation-of-metabolic-key-indicators-in-serum-of-dairy-cows-between-week-2-antepartum-and-week-12-pos.php |
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