A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region.
The greater Himalayan region demarcates two of the most prominent linguistic phyla in Asia: Tibeto-Burman and Indo-European. Previous genetic surveys, mainly using Y-chromosome polymorphisms and/or mitochondrial DNA polymorphisms suggested a substantially reduced geneflow between populations belongi...
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| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3948894?pdf=render |
| _version_ | 1818505205431402496 |
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| author | Thirsa Kraaijenbrink Kristiaan J van der Gaag Sofia B Zuniga Yali Xue Denise R Carvalho-Silva Chris Tyler-Smith Mark A Jobling Emma J Parkin Bing Su Hong Shi Chun-Jie Xiao Wen-Ru Tang V K Kashyap R Trivedi T Sitalaximi Jheelam Banerjee Karma Tshering of Gaselô Nirmal M Tuladhar Jean-Robert M L Opgenort George L van Driem Guido Barbujani Peter de Knijff |
| author_facet | Thirsa Kraaijenbrink Kristiaan J van der Gaag Sofia B Zuniga Yali Xue Denise R Carvalho-Silva Chris Tyler-Smith Mark A Jobling Emma J Parkin Bing Su Hong Shi Chun-Jie Xiao Wen-Ru Tang V K Kashyap R Trivedi T Sitalaximi Jheelam Banerjee Karma Tshering of Gaselô Nirmal M Tuladhar Jean-Robert M L Opgenort George L van Driem Guido Barbujani Peter de Knijff |
| author_sort | Thirsa Kraaijenbrink |
| collection | DOAJ |
| description | The greater Himalayan region demarcates two of the most prominent linguistic phyla in Asia: Tibeto-Burman and Indo-European. Previous genetic surveys, mainly using Y-chromosome polymorphisms and/or mitochondrial DNA polymorphisms suggested a substantially reduced geneflow between populations belonging to these two phyla. These studies, however, have mainly focussed on populations residing far to the north and/or south of this mountain range, and have not been able to study geneflow patterns within the greater Himalayan region itself. We now report a detailed, linguistically informed, genetic survey of Tibeto-Burman and Indo-European speakers from the Himalayan countries Nepal and Bhutan based on autosomal microsatellite markers and compare these populations with surrounding regions. The genetic differentiation between populations within the Himalayas seems to be much higher than between populations in the neighbouring countries. We also observe a remarkable genetic differentiation between the Tibeto-Burman speaking populations on the one hand and Indo-European speaking populations on the other, suggesting that language and geography have played an equally large role in defining the genetic composition of present-day populations within the Himalayas. |
| first_indexed | 2024-12-10T21:47:32Z |
| format | Article |
| id | doaj.art-6e8dbd1a46314f50a20461f8786b10ef |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T21:47:32Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-6e8dbd1a46314f50a20461f8786b10ef2022-12-22T01:32:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0193e9153410.1371/journal.pone.0091534A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region.Thirsa KraaijenbrinkKristiaan J van der GaagSofia B ZunigaYali XueDenise R Carvalho-SilvaChris Tyler-SmithMark A JoblingEmma J ParkinBing SuHong ShiChun-Jie XiaoWen-Ru TangV K KashyapR TrivediT SitalaximiJheelam BanerjeeKarma Tshering of GaselôNirmal M TuladharJean-Robert M L OpgenortGeorge L van DriemGuido BarbujaniPeter de KnijffThe greater Himalayan region demarcates two of the most prominent linguistic phyla in Asia: Tibeto-Burman and Indo-European. Previous genetic surveys, mainly using Y-chromosome polymorphisms and/or mitochondrial DNA polymorphisms suggested a substantially reduced geneflow between populations belonging to these two phyla. These studies, however, have mainly focussed on populations residing far to the north and/or south of this mountain range, and have not been able to study geneflow patterns within the greater Himalayan region itself. We now report a detailed, linguistically informed, genetic survey of Tibeto-Burman and Indo-European speakers from the Himalayan countries Nepal and Bhutan based on autosomal microsatellite markers and compare these populations with surrounding regions. The genetic differentiation between populations within the Himalayas seems to be much higher than between populations in the neighbouring countries. We also observe a remarkable genetic differentiation between the Tibeto-Burman speaking populations on the one hand and Indo-European speaking populations on the other, suggesting that language and geography have played an equally large role in defining the genetic composition of present-day populations within the Himalayas.http://europepmc.org/articles/PMC3948894?pdf=render |
| spellingShingle | Thirsa Kraaijenbrink Kristiaan J van der Gaag Sofia B Zuniga Yali Xue Denise R Carvalho-Silva Chris Tyler-Smith Mark A Jobling Emma J Parkin Bing Su Hong Shi Chun-Jie Xiao Wen-Ru Tang V K Kashyap R Trivedi T Sitalaximi Jheelam Banerjee Karma Tshering of Gaselô Nirmal M Tuladhar Jean-Robert M L Opgenort George L van Driem Guido Barbujani Peter de Knijff A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. PLoS ONE |
| title | A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. |
| title_full | A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. |
| title_fullStr | A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. |
| title_full_unstemmed | A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. |
| title_short | A linguistically informed autosomal STR survey of human populations residing in the greater Himalayan region. |
| title_sort | linguistically informed autosomal str survey of human populations residing in the greater himalayan region |
| url | http://europepmc.org/articles/PMC3948894?pdf=render |
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