Listening to speech with a guinea pig-to-human brain-to-brain interface
Abstract Nicolelis wrote in his 2003 review on brain-machine interfaces (BMIs) that the design of a successful BMI relies on general physiological principles describing how neuronal signals are encoded. Our study explored whether neural information exchanged between brains of different species is po...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-90823-1 |
| _version_ | 1819036226882109440 |
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| author | Claus-Peter Richter Petrina La Faire Xiaodong Tan Pamela Fiebig David M. Landsberger Alan G. Micco |
| author_facet | Claus-Peter Richter Petrina La Faire Xiaodong Tan Pamela Fiebig David M. Landsberger Alan G. Micco |
| author_sort | Claus-Peter Richter |
| collection | DOAJ |
| description | Abstract Nicolelis wrote in his 2003 review on brain-machine interfaces (BMIs) that the design of a successful BMI relies on general physiological principles describing how neuronal signals are encoded. Our study explored whether neural information exchanged between brains of different species is possible, similar to the information exchange between computers. We show for the first time that single words processed by the guinea pig auditory system are intelligible to humans who receive the processed information via a cochlear implant. We recorded the neural response patterns to single-spoken words with multi-channel electrodes from the guinea inferior colliculus. The recordings served as a blueprint for trains of biphasic, charge-balanced electrical pulses, which a cochlear implant delivered to the cochlear implant user’s ear. Study participants completed a four-word forced-choice test and identified the correct word in 34.8% of trials. The participants' recognition, defined by the ability to choose the same word twice, whether right or wrong, was 53.6%. For all sessions, the participants received no training and no feedback. The results show that lexical information can be transmitted from an animal to a human auditory system. In the discussion, we will contemplate how learning from the animals might help developing novel coding strategies. |
| first_indexed | 2024-12-21T08:02:10Z |
| format | Article |
| id | doaj.art-6e92f167ed454de39e23219ab2bbc6be |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T08:02:10Z |
| publishDate | 2021-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-6e92f167ed454de39e23219ab2bbc6be2022-12-21T19:10:53ZengNature PortfolioScientific Reports2045-23222021-06-0111111410.1038/s41598-021-90823-1Listening to speech with a guinea pig-to-human brain-to-brain interfaceClaus-Peter Richter0Petrina La Faire1Xiaodong Tan2Pamela Fiebig3David M. Landsberger4Alan G. Micco5Department of Otolaryngology, Northwestern UniversityDepartment of Otolaryngology, Northwestern UniversityDepartment of Otolaryngology, Northwestern UniversityDepartment of Otolaryngology, Northwestern UniversityDepartment of Otolaryngology, New York University Grossman School of MedicineDepartment of Otolaryngology, Northwestern UniversityAbstract Nicolelis wrote in his 2003 review on brain-machine interfaces (BMIs) that the design of a successful BMI relies on general physiological principles describing how neuronal signals are encoded. Our study explored whether neural information exchanged between brains of different species is possible, similar to the information exchange between computers. We show for the first time that single words processed by the guinea pig auditory system are intelligible to humans who receive the processed information via a cochlear implant. We recorded the neural response patterns to single-spoken words with multi-channel electrodes from the guinea inferior colliculus. The recordings served as a blueprint for trains of biphasic, charge-balanced electrical pulses, which a cochlear implant delivered to the cochlear implant user’s ear. Study participants completed a four-word forced-choice test and identified the correct word in 34.8% of trials. The participants' recognition, defined by the ability to choose the same word twice, whether right or wrong, was 53.6%. For all sessions, the participants received no training and no feedback. The results show that lexical information can be transmitted from an animal to a human auditory system. In the discussion, we will contemplate how learning from the animals might help developing novel coding strategies.https://doi.org/10.1038/s41598-021-90823-1 |
| spellingShingle | Claus-Peter Richter Petrina La Faire Xiaodong Tan Pamela Fiebig David M. Landsberger Alan G. Micco Listening to speech with a guinea pig-to-human brain-to-brain interface Scientific Reports |
| title | Listening to speech with a guinea pig-to-human brain-to-brain interface |
| title_full | Listening to speech with a guinea pig-to-human brain-to-brain interface |
| title_fullStr | Listening to speech with a guinea pig-to-human brain-to-brain interface |
| title_full_unstemmed | Listening to speech with a guinea pig-to-human brain-to-brain interface |
| title_short | Listening to speech with a guinea pig-to-human brain-to-brain interface |
| title_sort | listening to speech with a guinea pig to human brain to brain interface |
| url | https://doi.org/10.1038/s41598-021-90823-1 |
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