Gut microbiota and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study

Gut microbiota and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study

Abstract Background Although previous studies have suggested a close association between gut microbiota (GM) and intervertebral disc degeneration (IVDD), the causal relationship between them remains unclear. Hence, we thoroughly investigate their causal relationship by means of a two-sample Mendelia...

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Bibliographic Details
Main Authors: Ziming Geng, Jian Wang, Guangdong Chen, Jianchao Liu, Jie Lan, Zepei Zhang, Jun Miao
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Gut microbiota
Intervertebral disc degeneration
Low back pain
Causal relationship
Mendelian randomization
MiBioGen
Online Access:https://doi.org/10.1186/s13018-023-04081-0

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