Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences
Background The comparisons between open surgery and minimally invasive surgery for treatment of large adrenal tumor (LAT) are still lacking. In this study, we attempted to explore the safety and effectiveness of laparoscopic treatment of LAT by comparing the outcomes between open adrenalectomy (OA)...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-08-01
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| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/08941939.2020.1719243 |
| _version_ | 1797684607466864640 |
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| author | Juping Zhao Wenming Ma Jialing Xie Jun Dai Xin Huang Chen Fang Wei He Fukang Sun |
| author_facet | Juping Zhao Wenming Ma Jialing Xie Jun Dai Xin Huang Chen Fang Wei He Fukang Sun |
| author_sort | Juping Zhao |
| collection | DOAJ |
| description | Background The comparisons between open surgery and minimally invasive surgery for treatment of large adrenal tumor (LAT) are still lacking. In this study, we attempted to explore the safety and effectiveness of laparoscopic treatment of LAT by comparing the outcomes between open adrenalectomy (OA) and laparoscopic adrenalectomy (LA). Methods From 2003 to 2018, 78 LAT patients underwent tumor resection by OA or LA method at a single academic institution. Data were retrospectively collected and analyzed. Results The median largest diameter of LAT was 10.0 (IQR 9.0–13.4) cm. The median operation time in OA group was 215 (IQR 180–240) min versus 180 (IQR 135–245) min in LA group (P = 0.042). The median blood loss in OA group was 1000 (IQR 625–1500) ml versus 200 (IQR 100–700) ml in LA group (P < 0.001). The median Clavien–Dindo score in OA group was 2 (IQR 2–4) versus 0 (IQR 0–4) in LA group (P = 0.035). On univariate and multivariate analysis, the largest diameter of tumor was significantly associated with operation time, blood loss, and recovery time (P < 0.05). Conclusions Laparoscopic treatment of LAT was found to be safe and feasible in experienced hands and can replace open surgeries in most cases. |
| first_indexed | 2024-03-12T00:33:05Z |
| format | Article |
| id | doaj.art-6ea1a169661a4619956f77fe035d8f35 |
| institution | Directory Open Access Journal |
| issn | 0894-1939 1521-0553 |
| language | English |
| last_indexed | 2024-03-12T00:33:05Z |
| publishDate | 2021-08-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj.art-6ea1a169661a4619956f77fe035d8f352023-09-15T10:07:32ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532021-08-0134995796210.1080/08941939.2020.17192431719243Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center ExperiencesJuping Zhao0Wenming Ma1Jialing Xie2Jun Dai3Xin Huang4Chen Fang5Wei He6Fukang Sun7Department of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Pathology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalDepartment of Urology, Shanghai JiaoTong University School of Medicine, Ruijin HospitalBackground The comparisons between open surgery and minimally invasive surgery for treatment of large adrenal tumor (LAT) are still lacking. In this study, we attempted to explore the safety and effectiveness of laparoscopic treatment of LAT by comparing the outcomes between open adrenalectomy (OA) and laparoscopic adrenalectomy (LA). Methods From 2003 to 2018, 78 LAT patients underwent tumor resection by OA or LA method at a single academic institution. Data were retrospectively collected and analyzed. Results The median largest diameter of LAT was 10.0 (IQR 9.0–13.4) cm. The median operation time in OA group was 215 (IQR 180–240) min versus 180 (IQR 135–245) min in LA group (P = 0.042). The median blood loss in OA group was 1000 (IQR 625–1500) ml versus 200 (IQR 100–700) ml in LA group (P < 0.001). The median Clavien–Dindo score in OA group was 2 (IQR 2–4) versus 0 (IQR 0–4) in LA group (P = 0.035). On univariate and multivariate analysis, the largest diameter of tumor was significantly associated with operation time, blood loss, and recovery time (P < 0.05). Conclusions Laparoscopic treatment of LAT was found to be safe and feasible in experienced hands and can replace open surgeries in most cases.http://dx.doi.org/10.1080/08941939.2020.1719243large adrenal tumorlaparoscopyadrenalectomy |
| spellingShingle | Juping Zhao Wenming Ma Jialing Xie Jun Dai Xin Huang Chen Fang Wei He Fukang Sun Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences Journal of Investigative Surgery large adrenal tumor laparoscopy adrenalectomy |
| title | Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences |
| title_full | Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences |
| title_fullStr | Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences |
| title_full_unstemmed | Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences |
| title_short | Laparoscopic Treatment of Large Adrenal Tumor is Safe and Effective? A Single Center Experiences |
| title_sort | laparoscopic treatment of large adrenal tumor is safe and effective a single center experiences |
| topic | large adrenal tumor laparoscopy adrenalectomy |
| url | http://dx.doi.org/10.1080/08941939.2020.1719243 |
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