Integrative Modeling of Macromolecular Assemblies from Low to Near-Atomic Resolution

Integrative Modeling of Macromolecular Assemblies from Low to Near-Atomic Resolution

While conventional high-resolution techniques in structural biology are challenged by the size and flexibility of many biological assemblies, recent advances in low-resolution techniques such as cryo-electron microscopy (cryo-EM) and small angle X-ray scattering (SAXS) have opened up new avenues to...

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Bibliographic Details
Main Authors: Xiaojun Xu, Chunli Yan, Robert Wohlhueter, Ivaylo Ivanov
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Integrative modeling
Hybrid modeling
Molecular dynamics flexible fitting (MDFF)
Small angle X-ray scattering (SAXS)
Electron microscopy (EM)
DNA replication and repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037015000409

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