Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle
<p>Abstract</p> <p>Chronic cardiac insufficiency was associated with a malignant peripheral nerve sheath tumor in a cow. An eight-year-old cow developed a progressive condition (over a period of three months) characterized by an enhanced abdominal volume, reluctance to move, a posi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2013-01-01
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| Series: | Acta Veterinaria Scandinavica |
| Subjects: | |
| Online Access: | http://www.actavetscand.com/content/55/1/7 |
| _version_ | 1830274282424369152 |
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| author | Pavarini Saulo Petinatti Gomes Danilo Carloto Bandinelli Marcele Bettim Wouters Flademir Sonne Luciana Driemeier David Farias da Cruz Cláudio Estêvão |
| author_facet | Pavarini Saulo Petinatti Gomes Danilo Carloto Bandinelli Marcele Bettim Wouters Flademir Sonne Luciana Driemeier David Farias da Cruz Cláudio Estêvão |
| author_sort | Pavarini Saulo Petinatti |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Chronic cardiac insufficiency was associated with a malignant peripheral nerve sheath tumor in a cow. An eight-year-old cow developed a progressive condition (over a period of three months) characterized by an enhanced abdominal volume, reluctance to move, a positive jugular pulse, watery diarrhea and death. At necropsy, moderate subcutaneous edema and an enhanced hepatic lobular pattern were observed. A 23x20x11 cm firm, grayish-white mass adhered to and infiltrated the right atrium. Multiple firm, yellowish-white nodules of 0.5 to 12 cm in diameter were diffusely scattered in the epicardium and parietal pericardium. Histologically, the tumor was poorly circumscribed with foci of infiltration of the myocardium. The neoplastic cells had two major histologic patterns, Antoni types A and B. Within occasional foci, pleomorphic cells with an epithelioid appearance were present in addition to multinucleated cells with periodic acid Schiff (PAS)-positive cytoplasmic globules. Foci of cartilaginous and granular differentiations were interspersed among the neoplastic cells. Multiple vessels presented wall hyalinization and tumoral embolus. Large necrotic foci with mineralization and cholesterol clefts were also observed. Immunohistochemically, the tumor was positive for S100 protein, vimentin and neuron-specific enolase labeling.</p> |
| first_indexed | 2024-12-19T00:02:13Z |
| format | Article |
| id | doaj.art-6ea6364fc5e742a6a9880594ee0abacf |
| institution | Directory Open Access Journal |
| issn | 1751-0147 |
| language | English |
| last_indexed | 2024-12-19T00:02:13Z |
| publishDate | 2013-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Veterinaria Scandinavica |
| spelling | doaj.art-6ea6364fc5e742a6a9880594ee0abacf2022-12-21T20:46:26ZengBMCActa Veterinaria Scandinavica1751-01472013-01-01551710.1186/1751-0147-55-7Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattlePavarini Saulo PetinattiGomes Danilo CarlotoBandinelli Marcele BettimWouters FlademirSonne LucianaDriemeier DavidFarias da Cruz Cláudio Estêvão<p>Abstract</p> <p>Chronic cardiac insufficiency was associated with a malignant peripheral nerve sheath tumor in a cow. An eight-year-old cow developed a progressive condition (over a period of three months) characterized by an enhanced abdominal volume, reluctance to move, a positive jugular pulse, watery diarrhea and death. At necropsy, moderate subcutaneous edema and an enhanced hepatic lobular pattern were observed. A 23x20x11 cm firm, grayish-white mass adhered to and infiltrated the right atrium. Multiple firm, yellowish-white nodules of 0.5 to 12 cm in diameter were diffusely scattered in the epicardium and parietal pericardium. Histologically, the tumor was poorly circumscribed with foci of infiltration of the myocardium. The neoplastic cells had two major histologic patterns, Antoni types A and B. Within occasional foci, pleomorphic cells with an epithelioid appearance were present in addition to multinucleated cells with periodic acid Schiff (PAS)-positive cytoplasmic globules. Foci of cartilaginous and granular differentiations were interspersed among the neoplastic cells. Multiple vessels presented wall hyalinization and tumoral embolus. Large necrotic foci with mineralization and cholesterol clefts were also observed. Immunohistochemically, the tumor was positive for S100 protein, vimentin and neuron-specific enolase labeling.</p>http://www.actavetscand.com/content/55/1/7CattleImmunohistochemical proceduresNeoplasmMalignant schwannoma |
| spellingShingle | Pavarini Saulo Petinatti Gomes Danilo Carloto Bandinelli Marcele Bettim Wouters Flademir Sonne Luciana Driemeier David Farias da Cruz Cláudio Estêvão Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle Acta Veterinaria Scandinavica Cattle Immunohistochemical procedures Neoplasm Malignant schwannoma |
| title | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| title_full | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| title_fullStr | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| title_full_unstemmed | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| title_short | Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| title_sort | malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle |
| topic | Cattle Immunohistochemical procedures Neoplasm Malignant schwannoma |
| url | http://www.actavetscand.com/content/55/1/7 |
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