Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations
Abstract Background Angiogenesis is a process of formation of new blood vessels and is an important criteria demonstrated by cancer cells. Over a period of time, these cancer cells infect the other parts of the healthy body by a process called progression. The objective of the present article is to...
Main Authors: | Shailima Rampogu, Ayoung Baek, Amir Zeb, Keun Woo Lee |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-018-4050-1 |
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