An overview on the synthesis and anticancer properties of ethacrynic acid and their analogues

An overview on the synthesis and anticancer properties of ethacrynic acid and their analogues

Ethacrynic acid (EA, Edecrin) is a well-known diuretic drug used in the treatment of high blood pressure and the swelling caused by diseases such as congestive heart failure, liver failure, and kidney failure. EA has an α,β-unsaturated carbonyl unit which acts as a Michael acceptor involved in the i...

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Bibliographic Details
Main Authors:	Nabil El Brahmi, Abdelmoula El Abbouchi, Saïd El Kazzouli
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Results in Chemistry
Subjects:	Ethacrynic acid Diuretic Glutathione-S-transferase Anti-proliferative activity α β-unsaturated carbonyl
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211715623003569

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