Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999)
The susceptibility to penicillin of 111 Neisseria meningitidis strains was assessed by the agar-dilution procedure and serosubtypes were determined by a whole-cell enzyme-linked immunoassay using monoclonal antibodies reagents. Thirty-five isolates showed reduced sensitivity to penicillin (MIC >...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2001-05-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000400014 |
| _version_ | 1797757119692275712 |
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| author | Jorge Sosa Rafael Llanes Daymi Guzmán Ibrahín Quintana Mayra Flores Oderay Gutiérrez |
| author_facet | Jorge Sosa Rafael Llanes Daymi Guzmán Ibrahín Quintana Mayra Flores Oderay Gutiérrez |
| author_sort | Jorge Sosa |
| collection | DOAJ |
| description | The susceptibility to penicillin of 111 Neisseria meningitidis strains was assessed by the agar-dilution procedure and serosubtypes were determined by a whole-cell enzyme-linked immunoassay using monoclonal antibodies reagents. Thirty-five isolates showed reduced sensitivity to penicillin (MIC > or = 0.1 mg/l and <= 1 mg/l) and no resistant strains were detected. The most common phenotype was B:4:P1.15 (77.5%) and a rising trend of non-typeable and non-subtypeable strains was detected. The increase in levels of minimal inhibitory concentrations of meningococci to penicillin gives cause for concern and the increase in non-typeable and non-subtypeable isolation demand the use of molecular biology techniques for their typing. |
| first_indexed | 2024-03-12T18:11:22Z |
| format | Article |
| id | doaj.art-6ea8d8c9fba04a5ba83583d96cd48db3 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:11:22Z |
| publishDate | 2001-05-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-6ea8d8c9fba04a5ba83583d96cd48db32023-08-02T09:15:26ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602001-05-0196452352510.1590/S0074-02762001000400014Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999)Jorge SosaRafael LlanesDaymi GuzmánIbrahín QuintanaMayra FloresOderay GutiérrezThe susceptibility to penicillin of 111 Neisseria meningitidis strains was assessed by the agar-dilution procedure and serosubtypes were determined by a whole-cell enzyme-linked immunoassay using monoclonal antibodies reagents. Thirty-five isolates showed reduced sensitivity to penicillin (MIC > or = 0.1 mg/l and <= 1 mg/l) and no resistant strains were detected. The most common phenotype was B:4:P1.15 (77.5%) and a rising trend of non-typeable and non-subtypeable strains was detected. The increase in levels of minimal inhibitory concentrations of meningococci to penicillin gives cause for concern and the increase in non-typeable and non-subtypeable isolation demand the use of molecular biology techniques for their typing.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000400014Neisseria meningitidistypingreduced sensitivityCuba |
| spellingShingle | Jorge Sosa Rafael Llanes Daymi Guzmán Ibrahín Quintana Mayra Flores Oderay Gutiérrez Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) Memorias do Instituto Oswaldo Cruz Neisseria meningitidis typing reduced sensitivity Cuba |
| title | Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) |
| title_full | Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) |
| title_fullStr | Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) |
| title_full_unstemmed | Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) |
| title_short | Typing and susceptibility to penicillin of Neisseria meningitidis isolated from patients in Cuba (1993-1999) |
| title_sort | typing and susceptibility to penicillin of neisseria meningitidis isolated from patients in cuba 1993 1999 |
| topic | Neisseria meningitidis typing reduced sensitivity Cuba |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000400014 |
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